Nearly 14 percent of Americans suffer from chronic sinusitis and may have the following symptoms for 12 weeks or more; facial pain/pressure, facial congestion/fullness, nasal obstruction/blockage, thick nasal discharge/discolored post-nasal drainage, and periodic high fever. If antibiotics are not effective, these symptoms can lead to endoscopic sinus surgery to clear clogged sinuses.
Depression negatively impacts outcomes of care in chronic disease and has been associated with increased risk of morbidity and mortality. The prevalence of depression in patients with CRS is estimated to be in the range of 20-25%. High levels of depression in patients with CRS have been associated with increased utilization of healthcare resources, including more antibiotic use, physician visits, and missed workdays.
The study included face-to-face interviews with 76 patients who were enrolled prior to having endoscopic sinus surgery and followed postoperatively for at least 6 months post-operatively, including 8 patients with depression and 45 patients without depression.
Patients completed standard medical history intake documentation and underwent a physical examination. Demographic data and presence or absence of other clinical characteristics including nasal polyposis, asthma, allergies, aspirin intolerance, and smoking were documented and confirmed through physical examination when appropriate. Computed tomography and endoscopy findings were recorded and patients were asked to report a history of depression on the intake form and any anti-depressant medication they were using.
"Depression is common and underreported in patients with CRS. Depression significantly impacts patients' quality of life," said study author Jamie Litvack, MD, MS. "Depressed patients with CRS report worse disease-specific and general health-related QOL than other CRS patients, but experience comparable post-operative improvement in quality of life after endoscopic sinus surgery. Perhaps with better diagnosis and treatment of depression in this subset of patients, their outcomes of care can be further improved."
The Institutional Review Board at Oregon Health & Science University provided approval of study protocol and the informed consent process.
Otolaryngology – Head and Neck Surgery is the official scientific journal of the American Academy of Otolaryngology – Head and Neck Surgery Foundation (AAO-HNSF). The study's authors are Jamie R. Litvack, MD, MS; Jess C. Mace, MPH; Timothy L. Smith, MD, MPH.
Reporters who wish to obtain a copy of the study should contact Mary Stewart at 1-703-535-3762, or firstname.lastname@example.org.
About the AAO-HNS
The American Academy of Otolaryngology – Head and Neck Surgery (www.entnet.org), one of the oldest medical associations in the nation, represents nearly 12,000 physicians and allied health professionals who specialize in the diagnosis and treatment of disorders of the ears, nose, throat, and related structures of the head and neck. The Academy serves its members by facilitating the advancement of the science and art of medicine related to otolaryngology and by representing the specialty in governmental and socioeconomic issues. The organization's vision: "Empowering otolaryngologist-head and neck surgeons to deliver the best patient care."
Mary Stewart | EurekAlert!
Similarities found in cancer initiation in kidney, liver, stomach, pancreas
21.02.2018 | Washington University School of Medicine
'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
21.02.2018 | Life Sciences
21.02.2018 | Power and Electrical Engineering
21.02.2018 | Trade Fair News