Routine screening with echocardiogram can detect three times as many cases of rheumatic heart disease (RHD) as clinical examinations, offering a novel approach in preventing this common disease, according to a new study in Circulation. The study, conducted by cardiologists from Children's National Medical Center, is the largest single-population study in Africa. The August issue of Nature Reviews - Cardiology features a summary of the article in its Public Health feature.
The study screened nearly 5,000 school-aged children in Uganda and 130 had abnormal echocardiograms. After further evaluation at a hospital, 72 children were classified as having RHD, compared with just 23 children who met the diagnosis criteria for clinical evaluation. This represents a 400 percent increase in identification with an echocardiogram."What we found is that there were many children who had clinically silent RHD, which would have gone undetected without an echocardiogram," said Children's National's Andrea Beaton, MD, the lead author. "Echo screenings allow us to identify at-risk patients early, which in turn allows for early intervention to prevent more serious disease and complications."
Continue to support global efforts to treat subclinical RHD
RHD is the world's most common acquired cardiovascular disease, affecting approximately 15 million people, with a high incidence in developing countries. RHD is caused by repeated exposure to streptococcal bacteria, or strep throat, which is treated with antibiotics – when easily accessible. Repeated exposure to strep can lead to RHD, which carries many risks, including death. By identifying signs of RHD early, children can receive readily available antibiotics to prevent serious harm.
"Our study supports the World Heart Federation's new guidelines for using echocardiograms to diagnose RHD, so our hope is that more countries will adopt system-wide screening programs for this preventable disease," said Craig Sable, MD, a pediatric cardiologist at Children's National and senior author of the paper.
Dr. Sable has been leading cardiac screening programs in Uganda for the past 13 years. He and a large team from Children's National have screened more than 1,000 children and coordinated the care for more than 150 children in the United States. Dr. Sable has also led six cardiac surgery missions to Uganda since 2007 and coordinated additional surgical trips by other teams; more than 150 children have undergone open heart surgery in Uganda.
For copies of the study or for interviews, contact Emily Dammeyer or Emily Hartman, Public Relations: 202-476-4500About Children's National Medical Center
Emily Dammeyer | EurekAlert!
Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine
Flexible sensors can detect movement in GI tract
11.10.2017 | Massachusetts Institute of Technology
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
17.10.2017 | Life Sciences
17.10.2017 | Life Sciences
17.10.2017 | Earth Sciences