Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Echocardiogram screenings are effective in preventing rheumatic heart disease

Circulation study from Children's National Medical Center provides recommendations for preventing treatable condition

Routine screening with echocardiogram can detect three times as many cases of rheumatic heart disease (RHD) as clinical examinations, offering a novel approach in preventing this common disease, according to a new study in Circulation. The study, conducted by cardiologists from Children's National Medical Center, is the largest single-population study in Africa. The August issue of Nature Reviews - Cardiology features a summary of the article in its Public Health feature.

The study screened nearly 5,000 school-aged children in Uganda and 130 had abnormal echocardiograms. After further evaluation at a hospital, 72 children were classified as having RHD, compared with just 23 children who met the diagnosis criteria for clinical evaluation. This represents a 400 percent increase in identification with an echocardiogram.

"What we found is that there were many children who had clinically silent RHD, which would have gone undetected without an echocardiogram," said Children's National's Andrea Beaton, MD, the lead author. "Echo screenings allow us to identify at-risk patients early, which in turn allows for early intervention to prevent more serious disease and complications."

The team performed upwards of 250 screenings daily, making echocardiograms an efficient and effective means for screening. The authors' recommendations include:
Focus screening on children 10 years old in lower socioeconomic groups, to maximize limited resources
Provide a two-staged approach to RHD detection (initial echo screening followed by comprehensive follow up)

Continue to support global efforts to treat subclinical RHD

RHD is the world's most common acquired cardiovascular disease, affecting approximately 15 million people, with a high incidence in developing countries. RHD is caused by repeated exposure to streptococcal bacteria, or strep throat, which is treated with antibiotics – when easily accessible. Repeated exposure to strep can lead to RHD, which carries many risks, including death. By identifying signs of RHD early, children can receive readily available antibiotics to prevent serious harm.

"Our study supports the World Heart Federation's new guidelines for using echocardiograms to diagnose RHD, so our hope is that more countries will adopt system-wide screening programs for this preventable disease," said Craig Sable, MD, a pediatric cardiologist at Children's National and senior author of the paper.

Dr. Sable has been leading cardiac screening programs in Uganda for the past 13 years. He and a large team from Children's National have screened more than 1,000 children and coordinated the care for more than 150 children in the United States. Dr. Sable has also led six cardiac surgery missions to Uganda since 2007 and coordinated additional surgical trips by other teams; more than 150 children have undergone open heart surgery in Uganda.

For copies of the study or for interviews, contact Emily Dammeyer or Emily Hartman, Public Relations: 202-476-4500

About Children's National Medical Center

Children's National Medical Center in Washington, DC, has been serving the nation's children since 1870. Home to Children's Research Institute and the Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National is consistently ranked among the top pediatric hospitals by U.S.News & World Report and the Leapfrog Group. Children's National is a Magnet® designated hospital. With 303 beds and eight regional outpatient centers, Children's National is the only exclusive provider of acute pediatric services in the Washington metropolitan area. For more information, visit, or follow us on Facebook and Twitter.

Emily Dammeyer | EurekAlert!
Further information:

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Space observation with radar to secure Germany's space infrastructure

Satellites in near-Earth orbit are at risk due to the steady increase in space debris. But their mission in the areas of telecommunications, navigation or weather forecasts is essential for society. Fraunhofer FHR therefore develops radar-based systems which allow the detection, tracking and cataloging of even the smallest particles of debris. Satellite operators who have access to our data are in a better position to plan evasive maneuvers and prevent destructive collisions. From April, 25-29 2018, Fraunhofer FHR and its partners will exhibit the complementary radar systems TIRA and GESTRA as well as the latest radar techniques for space observation across three stands at the ILA Berlin.

The "traffic situation" in space is very tense: the Earth is currently being orbited not only by countless satellites but also by a large volume of space...

Im Focus: Researchers Discover New Anti-Cancer Protein

An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...

Im Focus: Researchers at Fraunhofer monitor re-entry of Chinese space station Tiangong-1

In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.

Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...

Im Focus: Alliance „OLED Licht Forum“ – Key partner for OLED lighting solutions

Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.

They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...

Im Focus: Mars' oceans formed early, possibly aided by massive volcanic eruptions

Oceans formed before Tharsis and evolved together, shaping climate history of Mars

A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

New solar solutions for sustainable buildings and cities

23.03.2018 | Event News

Virtual reality conference comes to Reutlingen

19.03.2018 | Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

Latest News

For graphite pellets, just add elbow grease

23.03.2018 | Materials Sciences

Unique communication strategy discovered in stem cell pathway controlling plant growth

23.03.2018 | Agricultural and Forestry Science

Sharpening the X-ray view of the nanocosm

23.03.2018 | Physics and Astronomy

Science & Research
Overview of more VideoLinks >>>