Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Early nutrition has a long-term metabolic impact

02.05.2011
Growth, hormonal profiles differ between breastfed, formula-fed infants

Nutrition during the first days or weeks of life may have long-term consequences on health, potentially via a phenomenon known as the metabolic programming effect, according to a study to be presented Monday, May 2, at the Pediatric Academic Societies (PAS) annual meeting in Denver.

Metabolic programming is the concept that differences in nutritional experiences at critical periods early in life can program a person's metabolism and health for the future.

In this study, researchers compared growth, body composition and blood pressure in three groups of healthy, full-term newborns in the Neonatal Department of Hospices Civils de Lyon, Claude Bernard University, Lyon, France. One group received only breast milk for the first four months of life. The two other groups were randomized to receive either a low-protein formula with 1.8 grams of protein/100 kilocalories (g/kcal) or a high-protein formula with 2.7 g/100 kcal. The protein content of both formulas was within the recommended levels of 1.8 to 3 g/100 kcal.

After four months, the formula-fed infants continued to receive the same formula, and the breastfed infants were assigned to the low-protein formula, if needed.

Researchers, who followed 234 children for three years, found that exclusive breastfeeding during the first weeks of life induced a specific pattern of growth and a specific metabolic profile, which appeared to differ in formula-fed infants. The protein content in infant formula may be a key factor in inducing these differences, according to study co-author Guy Putet, MD.

As early as 15 days of life, blood insulin levels were lower in breastfed infants than in formula-fed infants. These differences persisted at 4 months of age, but no differences were seen at 9 months.

Growth patterns also were different between groups during the first year of life, but by 3 years of age, there no longer was any difference in length, weight or body composition (fat mass, lean body mass) between groups. The exception was head circumference, which was slightly lower in the low-protein formula group but still well within the normal range.

At 3 years, an unexpected result was that diastolic and mean blood pressures were higher in the infants who had been fed the high-protein formula compared to the breastfed infants, Dr. Putet noted. However, these levels were still within the normal range.

"It appears that formula feeding induces differences in some hormonal profiles as well as in patterns of growth compared with breastfeeding," Dr. Putet said. "The long-term consequences of such changes are not well-understood in humans and may play a role in later health. Well-designed studies with long-term follow-up are needed."

If breastfeeding is not possible, Dr. Putet concluded, infants should be fed formulas that allow a growth pattern and a metabolic profile similar to that of breastfed infants.

To view the abstract, go to http://www.abstracts2view.com/pas/view.php?nu=PAS11L1_925.

The Pediatric Academic Societies (PAS) are four individual pediatric organizations who co-sponsor the PAS Annual Meeting – the American Pediatric Society, the Society for Pediatric Research, the Academic Pediatric Association, and the American Academy of Pediatrics. Members of these organizations are pediatricians and other health care providers who are practicing in the research, academic and clinical arenas. The four sponsoring organizations are leaders in the advancement of pediatric research and child advocacy within pediatrics, and all share a common mission of fostering the health and well being of children worldwide. For more information, visit www.pas-meeting.org. Follow news of the PAS meeting on Twitter at http://twitter.com/PedAcadSoc.

Susan Martin | EurekAlert!
Further information:
http://www.aap.org

Further reports about: PAS Pediatric academic blood pressure body composition formula-fed infants societies

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>