Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Drug-related morbidity in more than 10% of adults

23.04.2014

Twelve percent of adults in Sweden have diseases related to their use of medicines. But in four cases of ten it would have been possible to avoid the undesired effects. These are the conclusions of a thesis presented at the Sahlgrenska Academy, University of Gothenburg.

Katja Hakkarainen and her research colleagues have used 7,099 questionnaires and 4,970 patient medical records in Östergötland to map drug-related morbidity. Their work has included side effects, toxicity, the development of drug dependence, the insufficient effect of drugs, and lack of drug treatment.

The study is described in Katja Hakkarainen’s thesis, and shows that 19% of all adults in Sweden report some form of drug-related morbidity, while examination of the medical records gives a figure of 12%.

Two effects were most commonly reported: side effects, and insufficient effect of the drug.

Could have been prevented
At the same time, 20% of those who completed the questionnaire stated that they themselves, healthcare personnel or relatives could have prevented these effects.

Clinical experts who have examined the drug-related morbidity described in the medical records also came to the conclusion that 39%, or four cases of ten, could have been prevented.

“Our results show that drug-related morbidity is a significant public health problem, and that it must be prevented across the whole of the healthcare sector,” says Katja Hakkarainen, pharmacist and researcher at the Sahlgrenska Academy, University of Gothenburg.

Broader spectrum
Most previous studies in the field have focused on side effects associated with drug use. Katja Hakkarainen’s thesis, in contrast, draws attention to a broader spectrum of drug-related morbidity, including insufficient effects of medicines. The latter effect means, for example, that a potentially active drug has been taken at the wrong dose by the patient, or that it has been prescribed or used wrongly in some other way.

“The studies show that both those treating outpatients and those treating inpatients must become better at recognising drug-related morbidity. Further, new studies should be carried out by scientists, experts in safety and healthcare personnel together to develop preventative strategies,” says Katja Hakkarainen.

The questionnaire study was carried out in 2010, and the medical records were reviewed for year 2008, in collaboration with the Nordic School of Public Health NHV and Linköping University.

The thesis Prevalence and nature of adverse drug events and the potential for their prevention – Population-based studies among adults was successfully defended at a disputation on 21 March, 2014.

Link to the thesis: https://gupea.ub.gu.se/handle/2077/34825

Contact:
Katja Hakkarainen, pharmacist and research student at the Sahlgrenska Academy, University of Gothenburg
+46 (0)31 693989
katja.hakkarainen@nhv.se

Weitere Informationen:

http://sahlgrenska.gu.se/english/news_and_events/news/News_Detail/drug-related-m...

Krister Svahn | idw - Informationsdienst Wissenschaft

Further reports about: drug-related morbidity drugs effects medicines morbidity pharmacist

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>