Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Drug-related morbidity in more than 10% of adults

23.04.2014

Twelve percent of adults in Sweden have diseases related to their use of medicines. But in four cases of ten it would have been possible to avoid the undesired effects. These are the conclusions of a thesis presented at the Sahlgrenska Academy, University of Gothenburg.

Katja Hakkarainen and her research colleagues have used 7,099 questionnaires and 4,970 patient medical records in Östergötland to map drug-related morbidity. Their work has included side effects, toxicity, the development of drug dependence, the insufficient effect of drugs, and lack of drug treatment.

The study is described in Katja Hakkarainen’s thesis, and shows that 19% of all adults in Sweden report some form of drug-related morbidity, while examination of the medical records gives a figure of 12%.

Two effects were most commonly reported: side effects, and insufficient effect of the drug.

Could have been prevented
At the same time, 20% of those who completed the questionnaire stated that they themselves, healthcare personnel or relatives could have prevented these effects.

Clinical experts who have examined the drug-related morbidity described in the medical records also came to the conclusion that 39%, or four cases of ten, could have been prevented.

“Our results show that drug-related morbidity is a significant public health problem, and that it must be prevented across the whole of the healthcare sector,” says Katja Hakkarainen, pharmacist and researcher at the Sahlgrenska Academy, University of Gothenburg.

Broader spectrum
Most previous studies in the field have focused on side effects associated with drug use. Katja Hakkarainen’s thesis, in contrast, draws attention to a broader spectrum of drug-related morbidity, including insufficient effects of medicines. The latter effect means, for example, that a potentially active drug has been taken at the wrong dose by the patient, or that it has been prescribed or used wrongly in some other way.

“The studies show that both those treating outpatients and those treating inpatients must become better at recognising drug-related morbidity. Further, new studies should be carried out by scientists, experts in safety and healthcare personnel together to develop preventative strategies,” says Katja Hakkarainen.

The questionnaire study was carried out in 2010, and the medical records were reviewed for year 2008, in collaboration with the Nordic School of Public Health NHV and Linköping University.

The thesis Prevalence and nature of adverse drug events and the potential for their prevention – Population-based studies among adults was successfully defended at a disputation on 21 March, 2014.

Link to the thesis: https://gupea.ub.gu.se/handle/2077/34825

Contact:
Katja Hakkarainen, pharmacist and research student at the Sahlgrenska Academy, University of Gothenburg
+46 (0)31 693989
katja.hakkarainen@nhv.se

Weitere Informationen:

http://sahlgrenska.gu.se/english/news_and_events/news/News_Detail/drug-related-m...

Krister Svahn | idw - Informationsdienst Wissenschaft

Further reports about: drug-related morbidity drugs effects medicines morbidity pharmacist

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>