Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Don't worry, be healthy

10.07.2013
Johns Hopkins researchers link positive outlook to reduction in cardiac events such as heart attacks

People with cheerful temperaments are significantly less likely to suffer a coronary event such as a heart attack or sudden cardiac death, new Johns Hopkins research suggests.

Previous research has shown that depressed and anxious people are more likely to have heart attacks and to die from them than those whose dispositions are sunnier. But the Johns Hopkins researchers say their study shows that a general sense of well-being — feeling cheerful, relaxed, energetic and satisfied with life — actually reduces the chances of a heart attack.

A report on the research is published in the American Journal of Cardiology.

"If you are by nature a cheerful person and look on the bright side of things, you are more likely to be protected from cardiac events," says study leader Lisa R. Yanek, M.P.H., an assistant professor in the Division of General Internal Medicine at the Johns Hopkins University School of Medicine. "A happier temperament has an actual effect on disease and you may be healthier as a result."

Yanek cautioned that cheerful personalities are likely part of the temperament we are born with, not something we can easily change. While some have suggested it's possible that people lucky enough to have such a trait are also more likely to take better care of themselves and have more energy to do so, Yanek says her research shows that people with higher levels of well-being still had many risk factors for coronary disease but had fewer serious heart events.

She emphasized that the mechanisms behind the protective effect of positive well-being remain unclear. She also noted that her research offers insights into the interactions between mind and body, and could yield clues to those mechanisms in the future.

For the study, Yanek and her colleagues first looked at data from GeneSTAR (Genetic Study of Atherosclerosis Risk), a 25-year Johns Hopkins project sponsored by the National Institutes of Health to determine the roots of heart disease in people with a family history of coronary disease. They analyzed information gathered from 1,483 healthy siblings of people who had coronary events before the age of 60 and who were followed for five to 25 years. Siblings of people with early-onset coronary artery disease (CAD) are twice as likely of developing it themselves.

Among other things, study participants filled out well-being surveys and received a score, on a scale of 0 to 110, which gauged cheerful mood, level of concern about health, whether they were relaxed as opposed to anxious, energy level and life satisfaction. Over the course of an average 12-year follow-up, the researchers documented 208 coronary events — heart attacks, sudden cardiac death, acute coronary syndrome, and the need for stents or bypass surgery — in the sibling group.

The researchers found that participants' positive well-being was associated with a one-third reduction in coronary events; among those deemed at the highest risk for a coronary event, there was nearly a 50 percent reduction. The findings took into account other heart disease risk factors such as age, smoking, diabetes, high cholesterol levels and high blood pressure.

To validate their result, the researchers then looked at similar information in a general population using data from 5,992 participants in the first National Health and Nutrition Examination Survey (NHANES). In this population, over an average 16-year follow-up, there were 1,226 coronary events (20.5 percent). They found that this group also benefitted from a cheerful temperament, which reduced their risk of a coronary event by 13 percent.

The findings held whether the participants were white or African-American, men or women.

The research was supported in part by grants from the National Institutes of Health's National Institute of Nursing Research (NR02241), National Heart, Lung, and Blood Institute (R01 HL49762 and R01 HL59684) and National Center for Research Resources (M01 RR00052) to the Johns Hopkins University School of Medicine General Clinical Research Center.

Other Johns Hopkins researchers contributing to this study include Brian G. Kral, M.D., M.P.H.; Taryn F. Moy, M.S.; Dhananjay Vaidya, M.B.B.S., Ph.D., M.P.H.; Mariana Lazo, M.D., Ph.D., Sc.M.; Lewis C. Becker, M.D.; and Diane Becker, Sc.D., M.P.H.

For more information: http://www.genestarstudy.com

Johns Hopkins Medicine (JHM), headquartered in Baltimore, Maryland, is a $6.5 billion integrated global health enterprise and one of the leading health care systems in the United States. JHM unites physicians and scientists of the Johns Hopkins University School of Medicine with the organizations, health professionals and facilities of the Johns Hopkins Hospital and Health System. JHM's mission is to improve the health of the community and the world by setting the standard of excellence in medical education, research and clinical care. Diverse and inclusive, JHM educates medical students, scientists, health care professionals and the public; conducts biomedical research; and provides patient-centered medicine to prevent, diagnose and treat human illness. JHM operates six academic and community hospitals, four suburban health care and surgery centers, and more than 30 primary health care outpatient sites. The Johns Hopkins Hospital, opened in 1889, was ranked number one in the nation from 1990 to 2011 by U.S. News & World Report.

Media Contact: Stephanie Desmon
410-955-8665; sdesmon1@jhmi.edu
Helen Jones
410-502-9422; hjones49@jhmi.edu

Stephanie Desmon | EurekAlert!
Further information:
http://www.jhmi.edu

More articles from Health and Medicine:

nachricht Satellites, airport visibility readings shed light on troops' exposure to air pollution
09.12.2016 | Veterans Affairs Research Communications

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>