The findings are the first to show a difference between the two types of digital imaging when compared with screen film mammography and suggest that women should be informed of the potential for lower cancer detection with CR, the researchers said.
Digital mammography, which takes an electronic image of the breast that can be stored and sent electronically, has supplanted screen film mammography in recent years.
DR and CR are the two types of digital mammography offered. DR is an online system in which the detector is an integral part of the mammographic unit, and the digital image can be read by the system in real time. CR is an offline system that relies on a cassette-based removable detector. An external reading device is used to generate the digital image.
While numerous studies have been published comparing digital mammography with screen film mammography, less is known about the comparative effectiveness of DR and CR, according to Anna M. Chiarelli, Ph.D., senior scientist in Prevention and Cancer Control at Cancer Care Ontario in Toronto, Canada.
"Digital mammography was implemented progressively in Ontario starting in 2006, and since that time there's been no evidence in the literature to suggest that CR did not perform as well as DR," she said.
For the new study, Dr. Chiarelli and colleagues drew upon information from the Ontario Breast Screening Program (OBSP), initiated in 1990 to deliver breast screening to women between the ages of 50 and 74. The researchers identified three groups of women 50 to 74 years old who were screened between Jan. 1, 2008, and Dec. 31, 2009. A total of 403,688 women were screened by screen film mammography, while 220,520 had DR and 64,210 underwent CR. The women were followed for 12 months after screening.
DR detected 4.9 cancers per 1,000 mammograms, a figure almost identical to screen film mammography's rate of 4.8 cancers per 1,000 mammograms. However, CR's detection rate of 3.4 cancers per 1,000 mammograms was significantly lower.
"CR was 21 percent less effective than DR," Dr. Chiarelli said. "This could result in about 10 fewer cancers detected per 10,000 women screened."
The reason for the lower detection rates likely can be attributed to technical factors, Dr. Chiarelli added.
"There may be several technical reasons reported by others for the lower effectiveness of CR, including loss of spatial resolution, or sharpness, and increased image noise, or granularity," she said.
Dr. Chiarelli said the new results carry more weight than those of previous studies because of the larger number of women screened and the reliance on concurrent cohorts, or different groups followed over the same time period.
"Digital Compared with Screen-Film Mammography: Performance Measures in Concurrent Cohorts within an Organized Breast Screening Program." Collaborating with Dr. Chiarelli were Sarah A. Edwards, M.H.Sc., Maegan V. Prummel, M.P.H., Derek Muradali, M.D., Vicky Majpruz, M.Sc., Susan J. Done, M.B., B.Chir., Patrick Brown, Ph.D., Rene S. Shumak, M.D., and Martin J. Yaffe, Ph.D. The study was funded by the Canadian Institutes of Health Research.
Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc.
RSNA is an association of more than 51,000 radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)
For patient-friendly information on digital mammography, visit RadiologyInfo.org.
Linda Brooks | EurekAlert!
Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania
The strange double life of Dab2
10.01.2017 | University of Miami Miller School of Medicine
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...
Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
16.01.2017 | Power and Electrical Engineering
16.01.2017 | Information Technology
16.01.2017 | Power and Electrical Engineering