"People with diabetes are at risk for developing heart failure," says Henry Ford researcher and cardiologist David Lanfear, M.D., lead author of the study. "Diabetic adults die of heart disease two to four times more than those without diabetes.
"Our study data suggest that diabetic patients taking a particular class of medications are less likely to develop heart failure," adds Dr. Lanfear.
The results will be presented March 10 at the American College of Cardiology's annual meeting in San Francisco.
There are more than 25 million adults and children in the U.S. with diabetes, according to the American Diabetes Association. The ADA estimates that nearly 80 million people may be pre-diabetic, with nearly two million new cases diagnosed in adults in 2010. In 2007, diabetes contributed to a total of 231,404 deaths.
The retrospective study looked at 4,427 diabetic patients who were taking blood-sugar-lowering medications at Henry Ford Hospital between January 1, 2000 and July 1, 2012. Of these patients, 1,488 were taking GLP-1 medications (glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors) and 2,939 were not.
Over an observation time of 663 days, there were 281 hospitalizations, of which 184 were due to heart failure, and 158 deaths.
Results were adjusted for factors such as gender, age, race, coronary disease, heart failure, duration of diabetes, and the number of anti-diabetic medications, in order to identify the effect specifically attributable to taking GLP-1 medications. The researchers also looked at hospitalizations and deaths from all causes.
Use of GLP1 medications was associated with a reduced risk of hospitalization for heart failure or any other reason, as well as fewer deaths.
"These preliminary results look very promising," says Dr. Lanfear. "However this was a retrospective study and this subject needs further investigation."
The study was funded by the National Institutes of Health and Henry Ford Health System.
Sally Ann Brown | EurekAlert!
How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine
Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
19.01.2018 | Materials Sciences
19.01.2018 | Health and Medicine
19.01.2018 | Physics and Astronomy