The study, published in the April 1 issue of the journal Clinical Infectious Diseases, found the incidence of CA-MRSA in the Chicago area was six-fold higher among HIV-infected patients than it was among HIV-negative patients.
MRSA infections were once restricted to hospitals and long-term care facilities. However, transmission of MRSA has emerged in the community, causing infections in people without prior health care facility exposure. A majority of MRSA infections involve minor skin and soft tissue infections that are usually well treated with therapy, such as active antibiotics and drainage of infection. However, occasionally MRSA can lead to severe invasive and deadly disease, such as necrotizing pneumonia, fasciitis and bacteremia.
Using electronic data, the study authors retrospectively studied HIV-infected patients with CA-MRSA who received medical care during the period of 2000 to 2007 in the regional Cook County Health and Hospitals System. Researchers used patients' zip codes to examine where the cases were distributed geographically.
Overall incidence of CA-MRSA increased significantly for all populations in Cook County from the first period (2000- 2003) to the second period (2004-2007). The incidence increased four-fold from 61 cases to 253 cases per 100,000 HIV-negative patients and nearly four-fold from 411 cases to 1474 cases per 100,000 HIV-infected patients, respectively.
"HIV does not cause CA-MRSA, but our study shows an association between HIV and CA-MRSA. The next steps are to find out what is going on in the community to cause these infections," said study author Dr. Kyle Popovich, an infectious disease specialist at Rush University Medical Center. "We believe the risk may be amplified by overlapping community-based social networks of high-risk patients."
The traditional risk factors for CA-MRSA included populations where there is close person to person contact, such as children in daycare facilities, prisoners, athletes and military personnel.
The study did find the most significant predictors associated with CA-MRSA infection included living in zip codes with a high prevalence of former prison inmates, and living in alternative housing, such as a substance abuse treatment facility, shelters or subsidized housing.
However, the study authors note that CA-MRSA has spread throughout Cook County. When the epidemic first started it was clustered in certain zip codes, but is has now spread beyond that. During the first period, 10 percent of the zip codes in Cook County had a high rate of MRSA among HIV-infected patients. By the second time period, that percentage had jumped to 21 percent of zip codes.
"We are also are now seeing people with community MRSA that aren't in the traditional high risk groups," said Popovich. "We need to bring education to these communities and do more research to determine preventive strategies to address these intersecting epidemics."
Other researchers involved with the study include Dr. Robert A. Weinstein, Dr. Alla Aroutcheva, Dr. Bala Hota, and Thomas Rice, PhD. Funding for the study was provided by the Centers for Disease Control and Prevention.
Kim Waterman | EurekAlert!
Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
19.10.2017 | Materials Sciences
19.10.2017 | Materials Sciences
19.10.2017 | Physics and Astronomy