"I would suspect that about 2% of the complete population of Sweden are allergic to air oxidized linalool. That may not sound very much, but it is serious since linalool is so widely used as a fragrance ingredient.
Linalool is found in 60-80 percent of the perfumed hygiene products, washing up liquids and household cleaning agents that can be bought in the nearest supermarket, and it can be difficult for people who are allergic to avoid these products", says dermatologist Johanna Bråred Christensson, author of the thesis.
Around one person in five in Sweden has some form of contact allergy. Nickel is by far the most common substance that causes eczema, but the thesis shows that oxidized linalool occupies third place in the list, after nickel and cobalt.
"Linalool is present in many products around us, and this is probably the reason that contact allergy to this material is so common. Some people can shower with shower cream that contains linalool but never develop contact allergy, but we know that the risk increases as the exposure to t! he substance increases", says Johanna Bråred Christensson.
Linalool is a fragrance ingredient found naturally in lavender, mint, and other plants. Linalool breaks down when it comes into contact with oxygen, it becomes oxidized and can cause allergy. Manufacturers do include other substances in the products to delay this oxidation process, but allergenic substances can st! ill be formed from linalool when it is stored.
"One way of trying to minimize exposure to oxidized linalool is to avoid buying large packs of soap and shower cream, and always to replace the top after using a bottle", says Johanna Bråred Christensson.!
EU legislation states that manufacturers must specify on the labels of hygiene products whether they contain linalool. Previous studies have shown that oxidized linalool may cause contact allergy in about 1% of patients with eczema.BRIEF FACTS: COMMON CONTACT ALLERGENS
About 4000 undergraduate students and 1000 postgraduate students are enrolled at Sahlgrenska Academy. The staff is about 1500 persons. 850 of them are researchers and/or teachers.For more information contact:
Thesis title: Clinical and Experimental Studies on Oxidized Fragrance Terpenes as Contact AllergensThis thesis is based on the following papers:
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