The “disease with 1000 faces” is how multiple sclerosis (MS) is sometimes described. The reason for this name is that the clinical picture can differ dramatically from patient to patient – in terms of both the progression of the disease and the symptoms suffered.
They infected mice in the laboratory with a specific species of bacteria – listeria –, which shares a protein with oligodendrocytes, and observed the consequences when peripheral parts of the body were infected and when the infection was confined to the brain.
A kind of “trade-off” seems to be responsible for the difference in progression. The brain’s “decision” to allow the attack helps combat the pathogen. It would appear that the brain is applying the motto: better that a few infected cells are destroyed and nerve cell extensions are demyelized than that the pathogen spreads and may therefore kill the sufferer. However, in the absence of an infection with menacing pathogens, the brain “recognizes” that this is a misguided attack by killer T cells and destroys them. It is possible, though, that the brain may sometimes “overestimate” the threat posed by a microbial pathogen and may sacrifice the protective myelin sheath unnecessarily.Next steps
Gunnar Bartsch | idw
Satellites, airport visibility readings shed light on troops' exposure to air pollution
09.12.2016 | Veterans Affairs Research Communications
Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
09.12.2016 | Life Sciences
09.12.2016 | Ecology, The Environment and Conservation
09.12.2016 | Health and Medicine