Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Bridging research begins on pollen disease vaccine

Researchers at the RIKEN Research Center for Allergy and Immunology (RCAI) have begun bridging research for a vaccine to prevent and treat pollen disease caused by cedar pollen. Human clinical trials are still needed, but a vaccine appears to be in sight.

Researchers at the RIKEN Research Center for Allergy and Immunology (RCAI) have begun bridging research for a vaccine to prevent and treat pollen disease caused by cedar pollen. This is the first pollen disease vaccine developed so far, and consists of fused cryptomeria (cedar) pollen antigens created by genetic engineering.

Pollen disease is a serious and growing problem in Japan, where an estimated 16% of the population is suffering from symptoms of the allergy, many of whom are living in cities. Besides the discomfort experienced by sufferers, the condition causes work absences and other social problems. Some people have even suffered anaphylactic shock from cedar pollen. Until now there has been no treatment, except for allopathy, such as antihistamines to suppress the symptoms of itchy eyes, runny nose and sneezing. The new vaccine offers the hope of a cure, or at least a way to stimulate the immune system to regulate the allergic response caused by pollen disease.

Yasuyuki Ishii and his colleagues at RCAI’s Vaccine Design Research Team synthesized two kinds of principle cryptomeria pollen antigens using genetic engineering techniques. They found from animal trials that the vaccine was effective in both treating the condition and reducing the likelihood of anaphylactic shock, a risk when natural cryptomeria pollen is present.

The bridging study aims to expand research into clinical applications in humans, to determine dose levels and toxicity levels. Human clinical trials are still needed, but a vaccine to stimulate the immune system to fight cedar pollen disease appears to be in sight.

Saeko Okada | ResearchSEA
Further information:

More articles from Health and Medicine:

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

nachricht New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>