Breast cancer occurs more frequently in certain ethnic and racial groups, but the reasons behind these differences are not fully understood. To investigate the issue, Lisa Hines, ScD, of the University of Colorado at Colorado Springs led a study that considered how established breast cancer risk factors—including reproductive history, family history of breast cancer, menstrual history, hormone use, alcohol consumption, physical activity, height, and body mass index—might be involved in explaining some of the observed differences in the occurrence of breast cancer among racial and ethnic groups.
They studied breast cancer among women from the Southwest United States who were enrolled in the population-based, case-control 4-Corners Breast Cancer Study, which was designed to investigate factors that contribute to the difference in breast cancer incidence rates observed between Hispanic and non-Hispanic white women.
Prior studies have shown that non-Hispanic white women have a higher incidence of breast cancer than Hispanic women. In this current study, the researchers found that 62 percent to 75 percent of breast cancer cases among non-Hispanic white women were attributed to known breast cancer risk factors, compared with only 7 to 36 percent of cases among Hispanic women. Hispanic women were more likely to have characteristics associated with lower breast cancer risk, such as earlier age at first childbirth, having more children, shorter height, less hormone use, and less alcohol consumption. Among premenopausal women, taller height and family history of breast cancer were associated with increased risk in non-Hispanic white women but were not among Hispanic women. Among postmenopausal women, certain breast cancer risk factors in non-Hispanic whites (such as recent hormone therapy use and younger age at menarche) had no or only weak associations with breast cancer in Hispanics.
These findings suggest that many of the risk factors studied to date explain fewer of the breast cancer cases that arise in Hispanic women compared with non-Hispanic white women. "These differences are likely to contribute to disparities in breast cancer incidence rates, and could potentially reflect differences in breast cancer development among these ethnic groups," said Dr. Hines. For example, ethnic differences in genetic and environmental or lifestyle factors may affect individuals' susceptibility to the development of breast cancer.
The authors noted that the study's findings also indicate that the use of models to estimate a woman's risk of breast cancer that were developed from studies among non-Hispanic white populations need to be evaluated among other ethnic and racial populations.
Article: "Comparative analysis of breast cancer risk factors among Hispanic and non-Hispanic white women." Lisa M. Hines, Betsy Risendal, Martha L. Slattery, Kathy Baumgartner, Anna R. Giuliano, Carol Sweeney, Dana E. Rollison, and Tim Byers. Cancer; Published Online: April 26, 2010 (DOI: 10.1002/cncr.25154).
Author Contact: To arrange an interview with Prof. Hines please contact Tom Hutton, at the University of Colorado University Relations team on +1 (719) 255-3439 (office), +1 (719) 351-6519 (cell) or email@example.com
Claire Greenwell | EurekAlert!
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences