Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Brain cell transplants in early 2013

28.11.2012
As part of the European study TRANSEURO, five patients with Parkinson’s disease will undergo brain cell transplants at Skåne University Hospital in Lund, Sweden, in early 2013. These are the first operations of their kind in Europe for over 10 years.

The TRANSEURO study, which in Sweden is led by Lund University, is now taking a critical approach to the viability of cell therapy as a future treatment for Parkinson’s disease. Can we replace cells that die as a result of our most common neurological diseases? What are the therapies of the future for neurodegenerative diseases like Parkinson’s and Alzheimer’s?

Under the leadership of Professor of Neurology Olle Lindvall, brain researchers in Lund had already developed a method of transplanting nerve cells in the 1980s. In 1987, brain surgeon Stig Rehncrona operated on the very first patient. That study was historic and marked the first repair of the human nervous system. The news was cabled out to all the world’s media and the Swedish researchers soon graced the front page of the New York Times.

“Since the advances made in the 1980s and 1990s, the research field has encountered many obstacles. In the early 2000s, two American studies produced negative results, which meant that cell transplants for Parkinson’s disease came to a dead end”, says

Professor Anders Björklund, who in the 1980s was responsible for the ground-breaking discoveries in the laboratory.

Despite the unsatisfactory results presented in the American trials, cell therapy has still been seen to have effects that are entirely unique in the history of research on Parkinson’s. A third of the transplant patients have seen significant benefits of cell therapy over a very long period without medication, in some cases up to 20 years.

“For a disease with a very demanding medication regime, and for which the effects of the standard medication begin to diminish after 5–10 years, cell therapy represents a hope of a different life for many Parkinson’s sufferers”, says Professor Håkan Widner, who is in charge of patient recruitment in Lund.

“The results of TRANSEURO will play an important role in the immediate future of cell therapy as a viable treatment. We have scrutinized the failed American studies in an attempt to optimise the technique, improve patient selection and conduct more personalised follow-up. We are hopeful that the results will be different this time”, says Professor Widner.

Contact:
Håkan Widner, Adjunct Professor of Neurology at Lund University and consultant at Skåne University Hospital, tel: +46 46 171425

Anders Björklund, Professor of Neuroscience at Lund University, mobile: +46 703 146761

Helga Ekdahl Heun | idw
Further information:
http://www.vr.se

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>