Currently, patients with non-small cell lung cancer receive erlotinib after chemotherapy and other drugs have failed. But erlotinib will only shrink the tumour about 10 per cent of the time.
"This is a step in the right direction that will allow us to eventually personalize a patient's treatment," says Queen's University Oncology professor Lesley Seymour, who was the coordinating physician on the study. "At the moment, we give drugs to patients and if they respond, we are happy and continue the treatment. If they don't, we move on to another drug."
In addition to helping doctors select the best drug treatment for patients, tests such as these will reduce exposure to medical side effects like rash and diarrhea caused by erlotinib, and eliminate financial burdens for a drug that may not benefit the patient. Newer drugs such as erlotinib can cost thousands of dollars for a month of treatment.
The current research is a follow-up to an erlotinib clinical trial between 2001 and 2005 at the Queen's University-based National Cancer Institute of Canada Clinical Trials Group (NCIC CTG), which led to the approval of erlotinib in the treatment of non-small cell lung cancer.
In addition, blood and tissue samples collected in the original trials were used by David Carbone of the Vanderbilt-Ingram Cancer Center in Nashville to validate the blood tests. NCIC CTG and Queen's researchers also did the statistical analysis.
Professor Carbone presented his results on April 30 at the European Society for Medical Oncology Conference in Geneva, Switzerland.
Lung cancer is by far the deadliest form of cancer. There are 24,000 new cases of lung cancer diagnosed every year in Canada and 21,000 deaths.
Michael Onesi | EurekAlert!
Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection
24.10.2016 | Universität Basel
Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
24.10.2016 | Earth Sciences
24.10.2016 | Life Sciences
24.10.2016 | Physics and Astronomy