Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Blood glucose control more important for patients with diabetes than previously believed

11.05.2009
It is even more important than previously believed that patients with diabetes accurately maintain their blood glucose levels at a normal, low level.

Even small improvements can make a great difference in the long term. These are the conclusions of a thesis recently presented at the Sahlgrenska Academy, University of Gothenburg, Sweden.

The studies have been carried out by statistical analysis of patients' records for patients at several diabetes clinics in western Sweden. A large American study is also included in the thesis. New statistical methods and extensive data collection have made it possible to analyse and study in detail the effects of treatments in a long-term perspective.

"Our results show that the risk of complications 10-15 years after the start of treatment probably decreases significantly following even small improvements in blood glucose control. If the treatment of all Swedish diabetes patients could be even slightly improved, we believe that tens of thousands of cases of injuries to the eyes, kidneys, heart, nerves and brain could be prevented", says physician Marcus Lind, author of the thesis.

The thesis also shows by analysis of many patients' records from diabetes clinics in western Sweden from the period 1996-2004 that modern insulins give better control of blood glucose levels than older insulins. The records for patients who changed during the period of study from the older types of insulin (known as "regular" and "NPH" insulin) to the more modern types of insulin glargin (distributed under the trade name "Lantus®") and lispro (distributed under the trade name "Humalog®") were analysed particularly carefully.

"The analysis shows that the long-acting insulin glargin gives patients in normal diabetes care better blood glucose control than they would have achieved if they had continued with the NPH insulin. Similarly, the rapidly acting insulin lispro gives better blood glucose control than the traditional regular insulin", says Marcus Lind.

Patients' records for just over 4,000 patients from several hospitals in western Sweden were examined in the studies of insulin glargine, and just over 1,000 records for insulin lispro.

Link to thesis: http://hdl.handle.net/2077/19641

For more information contact:
Marcus Lind, Registered physician, telephone: +46 (0)522 92000, Mobile: +46 (0)73 831 1742, e-mail
Supervisor:
Associate professor Björn Eliasson, telephone: +46 (0)31 342 1000, Mobile: +46 (0)70 604 2380, e-mail
The thesis has been presented for the degree of Doctor of Philosophy (Medicine) at the Sahlgrenska Academy, Institute of Medicine.

Title of the thesis: Glycaemic control: evaluations of HbA1c as a risk factor and the effects of modern insulins in clinical practice

The thesis will be defended on Thursday 23 April, 1.00 pm, in the Arvid Carlsson lecture theatre, Academicum, Medicinaregatan 3, Göteborg, Sweden.

The thesis is available for download on the internet at: http://hdl.handle.net/2077/19641

BY: Elin Lindström Claessen
+46 31 786 3869

Helena Aaberg | idw
Further information:
http://www.gu.se/
http://hdl.handle.net/2077/19641

More articles from Health and Medicine:

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

nachricht The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>