Even small improvements can make a great difference in the long term. These are the conclusions of a thesis recently presented at the Sahlgrenska Academy, University of Gothenburg, Sweden.
The studies have been carried out by statistical analysis of patients' records for patients at several diabetes clinics in western Sweden. A large American study is also included in the thesis. New statistical methods and extensive data collection have made it possible to analyse and study in detail the effects of treatments in a long-term perspective.
"Our results show that the risk of complications 10-15 years after the start of treatment probably decreases significantly following even small improvements in blood glucose control. If the treatment of all Swedish diabetes patients could be even slightly improved, we believe that tens of thousands of cases of injuries to the eyes, kidneys, heart, nerves and brain could be prevented", says physician Marcus Lind, author of the thesis.
"The analysis shows that the long-acting insulin glargin gives patients in normal diabetes care better blood glucose control than they would have achieved if they had continued with the NPH insulin. Similarly, the rapidly acting insulin lispro gives better blood glucose control than the traditional regular insulin", says Marcus Lind.
Patients' records for just over 4,000 patients from several hospitals in western Sweden were examined in the studies of insulin glargine, and just over 1,000 records for insulin lispro.
Link to thesis: http://hdl.handle.net/2077/19641For more information contact:
Title of the thesis: Glycaemic control: evaluations of HbA1c as a risk factor and the effects of modern insulins in clinical practiceThe thesis will be defended on Thursday 23 April, 1.00 pm, in the Arvid Carlsson lecture theatre, Academicum, Medicinaregatan 3, Göteborg, Sweden.
The thesis is available for download on the internet at: http://hdl.handle.net/2077/19641BY: Elin Lindström Claessen
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.
Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
02.12.2016 | Medical Engineering
02.12.2016 | Agricultural and Forestry Science
02.12.2016 | Physics and Astronomy