Tuberculosis (TB) continues to pose a major global health threat. Someone in the world is newly infected with TB bacteria every second. Every year, more than 9 million people develop active TB and it claims about 2 million lives. In Canada, the overall incidence of TB has declined, but rates remain high among immigrants from endemic countries and among Aboriginal populations. Currently, Nunavut is facing the largest TB outbreak in the territory's 10- year history.
In the days leading up to World TB Day 2011 on March 24, a team of researchers from McGill University and the Research Institute of the McGill University Health Centre (RI MUHC) is officially launching the BCG World Atlas: a first-of-its-kind, easy-to-use, searchable website that provides free detailed information on current and past TB vaccination policies and practices for more than 180 countries.
"The Atlas is designed to be a useful resource for clinicians, policymakers and researchers alike," said co-author Dr. Madhukar Pai, who is an assistant professor at McGill's Dept. of Epidemiology, Biostatistics & Occupational Health and a researcher in the Respiratory Epidemiology and Clinical Research Unit at the Montreal Chest Institute and the RI MUHC. "It has important implications on diagnosing and treating TB and on the research that's being done on developing a new TB vaccine."
Pai is a senior author on a paper about the BCG World Atlas that will be published in the March edition of the journal PLoS Medicine.
The Bacille Calmette-Guérin (BCG) vaccine was introduced in 1921 and continues to be the only vaccine used to prevent TB. Despite nearly a century of use, the vaccine remains controversial, with known variations in efficacy, strains, policies and practices across the world. Clinicians need to be aware of the various BCG policies in different parts of the world, as well as changes to those policies over time, especially when dealing with foreign-born adults who were vaccinated as children and who are unlikely to have retained their childhood vaccination records.
Ms. Alice Zwerling, BCG Atlas project leader and PhD candidate in epidemiology at McGill, explained that BCG vaccination can cause false positives in the skin test that's routinely used to screen for latent TB. "As a clinician, if you're trying to interpret the skin test in a foreign-born person, you're going to want to know when the BCG vaccination was given back home and how many times it has been given. The Atlas provides this information and can help doctors decide on when to use the newly available blood tests for TB that are not affected by BCG vaccination," she added.
"I am pleased that the Public Health Agency of Canada (PHAC) could play a part in such an important project," said Dr. David Butler-Jones, Canada's Chief Public Health Officer and the head of PHAC, which provided funding for this project. "The BCG World Atlas will be a vital resource for practitioners across Canada, one that will help us prevent and control the spread of TB here at home."
The Atlas project began in 2007 with the compilation of detailed information on past and present BCG vaccination policies on as many countries as possible. The data were assembled through respondent-completed questionnaires, published papers, reports, government policy documents and data available from the World Health Organization Vaccine Preventable Diseases Monitoring System. The beta version of the site went live in 2008 and over the past year more than 6,000 visits have been recorded with a steady increase in traffic over time. The Atlas is constantly being updated and its authors welcome input from countries that are currently not covered.
About the paper:
Work on the BCG World Atlas was supported in part by the Public Health Agency of Canada (PHAC) and a team award from the National Sanitarium Association (NSA). Canada. Alice Zwerling is supported by a Canadian Institutes of Health Research (CIHR) Doctoral research award, and Madhukar Pai is supported by a CIHR New Investigator Award. The research team also included Dr. Marcel A. Behr, Mr. Aman Verma, Dr. Timothy Brewer and Dr. Dick Menzies.BCG ATLAS VIDEO:
Allison Flynn | EurekAlert!
'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS
New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
16.02.2018 | Information Technology
16.02.2018 | Health and Medicine
16.02.2018 | Physics and Astronomy