Doctors at Nationwide Children’s Hospital who perform weight loss surgery (bariatric surgery) on adolescents took a look at their patient population in a retrospective study published in the January 2012 print edition of Pediatric Blood & Cancer. They found that their patients had experienced a significant loss of excess body weight and showed improvement in many obesity-related diseases within the first one to two years following surgery.
Investigators performed a retrospective analysis of 15 morbidly obese adolescents (10 females and five males) who underwent Roux-en-Y gastric bypass between 2004 and 2009. They compared baseline clinical and demographic data with the same data collected one and two years after surgery.
Results showed that the adolescents experienced significant loss of excess body weight and improved or resolved several common obesity-related diseases during this time period. Four of five patients who were being treated for high blood pressure before surgery resolved their high blood pressure two years after the operation.
“We do not yet know whether the improvements of these patients will correspond to long-term resolution of weight-related diseases or reduce their risk for future weight-related diseases,” said the study’s author Marc Michalsky, MD, surgical director of Bariatric Surgery at Nationwide Children’s Hospital. “Although our findings suggest that the most significant metabolic impact occurred within the first post-operative year, findings may differ in studies involving more patients who are followed longer-term.”
Dr. Michalsky, who also chairs the American Society for Metabolic and Bariatric Surgery Pediatric Committee’s best practice guidelines, says that weight loss surgery should be a last resort for teenagers, but can be a very effective intervention.
“The argument is quite compelling that we really do need to be doing it this young to avoid the chronic burden of disease these patients will suffer from if nothing is done,” said Dr. Michalsky.
In the Center for Healthy Weight and Nutrition at Nationwide Children’s Hospital, Dr. Michalsky’s patients first go through several months of evaluation to see if patients are even candidates for weight loss surgery. This includes an introductory information session attended by the adolescent and parent, and assessments of the potential candidate by a number of staff in the Center including dieticians, bariatric nurse practitioners, psychologists, physical therapists and surgeons. Candidates for weight loss surgery are those that have gone through several failed attempts at diet and exercise regiments. These teenagers have significant organ damage and their quality of life is poor, Dr. Michalsky said.
“Bariatric surgery in adolescents is never a cosmetic procedure,” explained Dr. Michalsky who is also a faculty member at The Ohio State University College of Medicine. “These teens are very sick, they are suffering and they can benefit from weight loss surgery. Our study demonstrates the safety and efficacy of weight reduction surgery in morbidly obese adolescents.”
Nationwide Children’s is one of a few centers in the country involved in long-term clinical research of adolescent bariatric surgery, looking not only at what happens in the short-term post-surgery, but long-term as well.
Erin Pope | Newswise Science News
23.03.2017 | Technische Universität München
How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
23.03.2017 | Life Sciences
23.03.2017 | Power and Electrical Engineering
23.03.2017 | Earth Sciences