Results indicate that people with an apnea-hypopnea index (AHI), the average of the combined episodes of apnea and hypopnea that occur per hour of sleep, of over 15 had an increase in body mass index (BMI) of 0.52 kg/m2 compared to those with an AHI between 5 and 15, who saw an increase of 0.22 kg/m2.
According to lead author Mark Brown, MD, Department of Psychiatry at the University of Arizona College of Medicine in Tucson, people suffering from more severe OSA may be more likely to gain more weight than those with less severe OSA over time.
"OSA is a disorder characterized by decreases or cessation of breathing during sleep. Obesity is a known risk factor for the disorder; however, it is hypothesized that the effects of OSA itself may predispose patients to weight gain," said Brown.
The study included data from 3,001 men and women from the Sleep Heart Health Study (SHHS) with an average age of 62.19. Of the sample, 55.2 percent of participants were female and 76.1 percent were Caucasian. Participants were classified as having no (AHI of less than 5), moderate (AHI between 5 and 15), and severe OSA (AHI of over 15). Weight and polysomnograph information were collected. Linear regression was used to examine the association between AHI groups and the change in BMI over approximately five years. The final model was adjusted for age, gender, race, initial BMI and change in AHI over 5 years.
More information about OSA can be found at: http://www.aasmnet.org/Resources/FactSheets/SleepApnea.pdf
SLEEP 2009 will bring together an international body of 6,000 leading researchers and clinicians in the field of sleep medicine to present and discuss new findings and medical developments related to sleep and sleep disorders.
More than 1,300 research abstracts will be presented at SLEEP 2009, a joint venture of the AASM and the Sleep Research Society. The scientific meeting will bring to light new findings that enhance the understanding of the processes of sleep and aid the diagnosis and treatment of sleep disorders such as insomnia, narcolepsy and sleep apnea.Abstract Title: Sleep-Disorded Breathing and Weight Gain: The Sleep Heart Health Study.
Kelly Wagner | EurekAlert!
Biofilm discovery suggests new way to prevent dangerous infections
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Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
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Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
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