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Antioxidant in Substance from Honeybees May Protect Athletes from Overheating

A compound from honeybees known as propolis, the substance bees use to seal their hives, may protect against heat stress in athletes, according to an article in the Journal of Food Science, published by the Institute of Food Technologists.

Honeybee propolis, or bee glue, has been widely used as a folk medicine. An active ingredient in propolis known as caffeic acid phenethyl ester, or CAPE, has a broad spectrum of biological activities including antioxidant, anti-inflammatory and antiviral.

Hyperthermia, or heat stress, is considered to be the main factor underlying the early fatigue and dehydration seen during prolonged exercise in the heat. “Since hyperthermia and free radical generation are related to exercise-induced physical damage, it is reasonable to test whether an antioxidant can prevent or reduce hyperthermia-induced free radical generation and damage,” says lead researcher Yu-Jen Chen of Chinese Culture University in Taiwan.

Researchers examined blood from 30 competitive cyclists who engaged in endurance training for two to four years prior to the investigation. None participated in any competitions or intensive training or had any clinical illness or medical or surgical treatments four months prior to the study.

“CAPE rescued mononuclear cells from hyperthermia-induced cell death,” writes Yu-Jen Chen. “This implies that CAPE might not only promote athletic performance but also prevent injury secondary to endurance-exercise-induced hyperthermia.” In addition, researchers indicated that further human studies need to be conducted to solidify their findings.

About IFT
The Institute of Food Technologists (IFT) exists to advance the science of food. Our long-range vision is to ensure a safe and abundant food supply contributing to healthier people everywhere. Founded in 1939, IFT is a nonprofit scientific society with 20,000 individual members working in food science, food technology, and related professions in industry, academia, and government. IFT champions the use of sound science across the food value chain through knowledge sharing, education, and advocacy, encouraging the exchange of information, providing both formal and informal educational opportunities, and furthering the advancement of the profession. IFT has offices in Chicago, Illinois, and Washington, D.C. For additional information, please visit

Jeannie Houchins | Newswise Science News
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