Professor Steven Youngentob from the State University of New York Upstate Medical University, USA, led a team of researchers who investigated the social and behavioral effects of fetal ethanol exposure in adolescent and adult rats.
He said, “The findings by Amber Eade in my lab reveal that fetal ethanol exposure influences adolescent re-exposure, in part, by promoting interactions with intoxicated peers. These results highlight an important relationship between fetal and adolescent experiences that appears essential to the progressive development of alcohol abuse.”
Fetal ethanol experience is believed to train the developing sense of smell to find ethanol odor more attractive. The authors describe how, in both rats and humans, fetal exposure changes how the odor and flavor of ethanol are perceived.
They write, “ Such learning may be a fundamental feature of all mammalian species because it is important (from a survival standpoint) for the pre-weanling animal to accept and be attracted to the food sources consumed by the mother”. In this study the authors found that rats unexposed to ethanol were significantly less likely to follow an intoxicated peer than those with gestational experience.
The authors also found that the behavioural effects of fetal ethanol were not seen in otherwise unexposed adult rats. They say that this shows adolescence is a key time for perpetuating fetal experiences. According to Youngentob, “Such a proposition is clinically relevant since, in humans, adolescence is a key transition point for emergent patterns of alcohol abuse”.
Speculating further on this study’s implications for human problem drinking, Youngentob added, “Within the context of ‘at risk’ adolescents, prior exposure to ethanol may, among other things, worsen the consequences of alcohol-related social interaction by increasing teenagers’ propensity to engage in such settings”.
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University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
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Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
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Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
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20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy