A common test to diagnose gestational diabetes — a temporary condition which can harm both mother and child if left untreated — also has predictive power for Type II adult-onset diabetes, a new Tel Aviv University study finds.
Dr. Gabriel Chodick of Tel Aviv University's Department of Epidemiology and Preventive Medicine at the Sackler Faculty of Medicine has proven that women who "fail" the glucose challenge test, a series of four blood tests conducted over a single four-hour period, have a higher chance of developing adult onset diabetes later in life. In his latest research, reported in the journal Diabetic Medicine, Dr. Chodick found that nearly half the women who fail all four of the four-part tests, demonstrating an elevated blood sugar level, developed Type II diabetes within ten years.
Dr. Chodick's study statistically proves what has been anecdotally believed by healthcare practitioners in the past. "While doctors take this into consideration, there usually isn't close follow-up in the clinical setting," says Dr. Chodick. He says that women in the highest risk group (those who fail all four of the tests) should be given special counselling and intervention to prevent the onset of diabetes, which can greatly diminish quality of life and lead to adverse effects including heart disease, blindness and liver cancer.
An effective warning sign
In the retrospective study, Dr. Chodick, Dr. Varda Shalev and their colleagues collected data on more than 185,000 women in Israel who took the glucose challenge test, then acquired information from the health registry as to what percentage of these women contracted diabetes later in life.
Dr. Chodick and his colleagues ascertained that women who failed all four glucose challenge blood tests had a nearly 50% chance of developing Type II diabetes within the ten years following the test. Those who failed three of the four tests had a 20% overall chance of developing the disease within the same period.
"This is the first-ever study to show the long-term health of those who failed the glucose challenge test," says Dr. Chodick.
Stopping the diabetes clock
While doctors commonly advise that women with gestational diabetes exercise and supplement their diet with fiber and fruit (and, in the most extreme circumstances, take insulin injections), women who take the advice usually have the health of their child in mind, not themselves. After giving birth, they resume adverse eating and lifestyle habits.
Dr. Chodick, whose life’s work is focused on preventative medicine, hopes to change attitudes and policies through his new study. In the U.S., Israel and Europe, HMOs are considering the elimination of the glucose battery test from their covered procedures, says Dr. Chodick. If so, fetal health may be in danger. The test results also provide invaluable predictive information for women's health in the long run.
Gestational diabetes currently affects 3 to 5% of all pregnant women in the U.S., and rates are continuing to rise, Dr. Chodick says. "It's an epidemic that can be stopped with information and action."
Keep up with the latest AFTAU news on Twitter: http://www.twitter.com/AFTAUnews
George Hunka | EurekAlert!
Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center
Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
22.09.2017 | Life Sciences
22.09.2017 | Medical Engineering
22.09.2017 | Physics and Astronomy