Claudiu T. Supuran and colleagues explain that dandruff involves an excessive shedding of dead skin cells from the scalp. In people without dandruff, it takes about 30 days for a crop of new skin cells to mature, die and shed. In people with dandruff, it may take only 2-7 days.
Irritation by the scalp-dwelling fungus Malassezia globosa (M. globosa) is one cause of dandruff. Shampoos and other dandruff treatments contain anti-fungal agents, but the authors say new medicines are badly needed since the two existing compounds are not very effective at preventing and treating dandruff.
In the quest for a better treatment, Supuran's group identified an enzyme in M. globosa that is essential for the fungus's growth. Tests showed that sulfonamides, a family of existing antibiotic medicines, were more effective in preventing the fungus's growth than ketoconazole, a widely used anti-fungal medicine that is an ingredient in certain dandruff treatments. As a result of the study, the scientists believe that the enzyme is a prime target for developing better anti-dandruff medicines.
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
To automatically receive news releases from the American Chemical Society contact email@example.com.
Michael Bernstein | EurekAlert!
Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
24.01.2017 | Earth Sciences
24.01.2017 | Life Sciences
24.01.2017 | Physics and Astronomy