Siemens is improving diagnosis and treatment of diseases with a unique imaging system that locates metabolic processes using nuclear detectors and x-ray images with high accuracy.
Symbia IntevoTM*, the world's first xSPECT* system, integrates metabolic information from single photon emission computed tomography (SPECT) into computed tomography (CT) images.
Previously, SPECT/CT images had low spatial resolution and physicians needed extensive experience and additional follow-up studies to decide whether a metabolic anomaly reflected a tumor or other diseases. Symbia Intevo also enables physicians to determine tumor size and thus plan treatment and monitor outcomes.
During SPECT examinations, patients are given low doses of radiopharmaceuticals that emit radiation when they react with a particular body tissue. Different metabolic processes can thus be observed depending on the agent administered. To determine the location of a metabolic disorder in the body, SPECT information is overlaid with CT images showing the anatomy of the body.
Until now, the problem has been that SPECT examinations offer only low spatial resolution and the high-precision CT images have to be adapted to match them. It can happen that the resulting image no longer clearly shows whether the metabolic disorder observed is inside or outside the bone. It would initially be unclear whether the anomaly was caused by a tumor in the bone or something else, such as a soft tissue inflammation.
The developers at Siemens Healthcare have now integrated SPECT and CT data in such a way that the high spatial resolution of the x-ray images remains intact and the SPECT images are significantly improved. The two datasets are generated sequentially during reconstruction in the same device using reference parameters such as the position of the detectors relative to the patient.
New, iterative image reconstruction algorithms refine the data in several passes. It was not previously possible to perform such complex calculation processes at the high resolution used in the CT images. That's why, in addition to new software, Symbia Intevo is also equipped with a powerful 64-bit computer.
The precise xSPECT data also makes it possible to determine the volume of the radiopharmaceutical used. This means that physicians can observe the change in metabolic activity and check whether their treatment is working.
Symbia Intevo also utilizes state-of-the-art algorithms that use the CT measurements to assign each voxel (three-dimensional pixel) in the xSPECT image to a particular class-fatty tissue, soft tissue, air, or hard (external) and soft (internal) bone areas. This makes it easy to recognize the body part where the metabolic disorder is located.
* Symbia Intevo and xSPECT are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed.
Dr. Norbert Aschenbrenner | Siemens InnovationNews
3-D visualization of the pancreas -- new tool in diabetes research
15.03.2017 | Umea University
New PET radiotracer identifies inflammation in life-threatening atherosclerosis
02.03.2017 | Society of Nuclear Medicine
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
24.03.2017 | Materials Sciences
24.03.2017 | Physics and Astronomy
24.03.2017 | Physics and Astronomy