That's the goal of Johns Hopkins biomedical engineering undergraduates who've developed a noninvasive way to identify women with this dangerous blood disorder in developing nations. The device, HemoGlobe, is designed to convert the existing cell phones of health workers into a "prick-free" system for detecting and reporting anemia at the community level.
This conceptual image illustrates how the HemoGlobe anemia screening device, slipped onto a patient's finger, would connect with a health worker's cellphone to display the test results.
The device's sensor, placed on a patient's fingertip, shines different wavelengths of light through the skin to measure the hemoglobin level in the blood. On a phone's screen, a community health worker quickly sees a color-coded test result, indicating cases of anemia, from mild to moderate and severe.
If anemia is detected, a patient would be encouraged to follow a course of treatment, ranging from taking iron supplements to visiting a clinic or hospital for potentially lifesaving measures. After each test, the phone would send an automated text message with a summary of the results to a central server, which would produce a real-time map showing where anemia is prevalent. This information could facilitate follow-up care and help health officials to allocate resources where the need is most urgent.
Soumyadipta Acharya, an assistant research professor in Johns Hopkins' Department of Biomedical Engineering and the project's faculty advisor and principal investigator, said the device could be important in reducing anemia-related deaths in developing countries. International health experts estimate that anemia contributes to 100,000 maternal deaths and 600,000 newborn deaths annually.
"This device has the potential to be a game-changer," Acharya said. "It will equip millions of health care workers across the globe to quickly and safely detect and report this debilitating condition in pregnant women and newborns."
The HemoGlobe student inventors have estimated their cell phone-based systems could be produced for $10 to $20 each. At the recent Saving Lives at Birth: A Grand Challenge for Development competition, the potential public health benefits of this device won over the judges, who awarded a $250,000 seed grant to the Johns Hopkins students' project. The event, which attracted more than 500 entrants from 60 countries, was sponsored by prominent global health organizations, including the U.S. Agency for International Development and the Bill & Melinda Gates Foundation. Only 12 entrants received seed grants.
"When we thought about the big-name corporations and nonprofit groups we were competing against, we were amazed and surprised to find out that our team had won," said George Chen, 19, of Hacienda Heights, Calif., a sophomore majoring in biomedical engineering. Chen attended the July 14 announcement in Seattle, along with Acharya and team members Noah Greenbaum and Justin Rubin.
For a biomedical engineering design team class assignment, the students spent a year brainstorming and building a prototype. The seed grant will allow the team to refine its technology and support field testing next year in Kenya by Jhpiego, a Johns Hopkins affiliate that provides global health training and services for women and their families. Jhpiego sponsored the HemoGlobe project through a partnership with the university's Center for Bioengineering Innovation and Design.
Team member Greenbaum, 21, of Watchung, N.J, a senior majoring in biomedical and electrical engineering, has continued working on the anemia system this summer.
"The first year we just focused on proving that the technology worked," he said. "Now, we have a greater challenge: to prove that it can have a real impact by detecting anemia and making sure the mothers get the care they need."
The student inventors were looking for a new way to curb a stubborn health problem in developing nations. Anemia occurs when a person has too few healthy red blood cells, which carry critical oxygen throughout the body. This is often due to a lack of iron, and therefore a lack of hemoglobin, the iron-based protein that helps red blood cells store and release oxygen. Anemic mothers face many complications before and during birth, including death from blood loss associated with the delivery. In addition, a baby that survives a birth from an anemic mother may face serious health problems.
Health officials in developing countries have tried to respond by making iron supplements widely available. According to Acharya, however, the problem of anemia remains intractable. "So we looked at it from a different angle," he said.
In places where medical care is easily accessible, doctors routinely test pregnant women for anemia and prescribe treatment, including routine iron supplementation. But in developing regions where medical help is not always nearby, the condition may go undetected. Community health workers with limited training do, however, serve these areas.
"The team members realized that every community health worker already carries a powerful computer in their pocket -- their cell phone," Acharya said. "So we didn't have to build a computer for our screening device, and we didn't have to build a display. Our low-cost device will use the existing cell phones of health workers to estimate and report hemoglobin levels."
A provisional patent covering the invention has been obtained through the Johns Hopkins Technology Transfer office.
In addition to Chen, Greenbaum and Rubin, other Whiting School of Engineering students who have participated on the team are Guilherme Barros, William Chen, Judy Doong, Phillip Oh and David Yin.
Color graphics of the invention are available; contact Phil Sneiderman.Related links:
Phil Sneiderman | EurekAlert!
Further reports about: > Bioengineering > Biomedical > Design Thinking > End User Development > Ferchau Engineering > Gates Foundation > Grand Challenge > HemoGlobe > Hopkins > biomedical engineering > blood cell > cell phone > developing countries > global health > health problem > medical engineering > pregnant women > red blood cells
Skin patch dissolves 'love handles' in mice
18.09.2017 | Columbia University Medical Center
Medicine of the future: New microchip technology could be used to track 'smart pills'
13.09.2017 | California Institute of Technology
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
21.09.2017 | Physics and Astronomy
21.09.2017 | Life Sciences
21.09.2017 | Health and Medicine