A total of 245 patients (54 patients with cancer, 191 patients with no cancer) were analyzed. “Our study supports previous data showing that some sonographic features of thyroid nodules are suggestive of malignant nature and should lead to biopsy,” said Dorra Sellami, MD, lead author of the study.
“These features include microcalcifications (which increase the risk of cancer 16 folds), a shape taller than wide (increases the risk of cancer 3.7 folds) and hypoechogenicity (two-fold increase in risk of cancer). Other features may suggest that a nodule is benign, such as hyperechogenicity (40% increase in risk of cancer),” she said. “Current clinical guidelines recommend biopsy of all lesions greater than or equal to 10 mm. However, in our study of patients with no thyroid cancer, 49% had at least one nodule greater than or equal to 10 mm,” said Dr. Sellami.
“Very few thyroid nodules are obviously malignant or benign. Most thyroid nodules we see by ultrasound are indeterminate, and in order to rule out cancer, a fine needle aspiration is often recommended. This results in a ratio of ten benign nodules sampled for one cancer diagnosed,” she said.
“Our findings will help radiologists and clinicians determine which nodules are definitely not suspicious and can be watched. I think that our study is one step toward decreasing the number of invasive procedures in patients with benign thyroid nodules—while maintaining the same vigilance in detecting thyroid cancer in its early stages,” said Dr. Sellami.
This study will be presented at the 2009 ARRS Annual Meeting in Boston, MA, on Monday, April 27. For a copy of the full study, please contact Heather Curry via email at firstname.lastname@example.org.
The American Roentgen Ray Society (ARRS) was founded in 1900 and is the oldest radiology society in the United States. Its monthly journal, the American Journal of Roentgenology, began publication in 1906. Radiologists from all over the world attend the ARRS annual meeting to participate in instructional courses, scientific paper presentations and scientific and commercial exhibits related to the field of radiology. The Society is named after the first Nobel Laureate in Physics, Wilhelm Röentgen, who discovered the x-ray in 1895.
Heather Curry | EurekAlert!
Computer accurately identifies and delineates breast cancers on digital tissue slides
11.05.2017 | Case Western Reserve University
SPECT/CT combined with fluorescence imaging detects micrometastases
09.05.2017 | Society of Nuclear Medicine
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...
For the first time, scientists have succeeded in studying the strength of hydrogen bonds in a single molecule using an atomic force microscope. Researchers from the University of Basel’s Swiss Nanoscience Institute network have reported the results in the journal Science Advances.
Hydrogen is the most common element in the universe and is an integral part of almost all organic compounds. Molecules and sections of macromolecules are...
22.05.2017 | Event News
17.05.2017 | Event News
16.05.2017 | Event News
22.05.2017 | Materials Sciences
22.05.2017 | Life Sciences
22.05.2017 | Physics and Astronomy