As mammography screening has shifted to digital technology, a range of computed radiography (CR) and direct radiography (DR) systems have emerged. The photon-counting technique is a promising DR approach that uses a unique detector to decrease scattered radiation and noise, enabling dose reduction and making it a promising tool for screening.
"In population-based mammography screening, dose reducing techniques that don't compromise outcome parameters are desirable," said Walter Heindel, M.D., from the Department of Clinical Radiology at the University Hospital Muenster in Muenster, Germany.
For the study, Dr. Heindel and colleagues analyzed data from the mammography screening program in North Rhine-Westphalia, the most populous state in Germany. They compared the screening performance of a DR photon-counting scan system with those of statewide operating screening units using different digital technologies. During the study period (2009 – 2010), 13,312 women were examined using the photon-counting system, and 993,822 women were screened with either CR or DR systems alone.
The photon-counting technique had almost twice the detection rate of other methods for ductal carcinoma in situ (DCIS), an early, noninvasive form of disease. It had a higher DCIS detection rate than the statewide units and the conventional DR subgroup.
In addition, the mean average glandular radiation dose of the DR photon-counting scan system was significantly lower than the conventional DR systems with the individually used parameters of the automatic exposure control.
The study's large size distinguishes it from previous studies that compared the DR photon-counting scan system's performance with other approaches.
"To our knowledge, the study is different from previous ones as we examined the performance of the DR photon-counting scan mammography on a larger database with consideration of multiple parameters of screening," said study coauthor Stefanie Weigel, M.D., from the University Hospital Muenster.
The photon-counting technique also offers lateral dose modulation during the image acquisition, which can help account for differences in breast density. Cancer often is more difficult to detect in women with dense breasts."The innovative photon-counting technique offers further research potential," Dr. Heindel said. "One future research direction is the application of spectral imaging for quantification of breast glandular tissue, addressing the problem of breast density."
Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc.
RSNA is an association of more than 53,000 radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill.
For patient-friendly information on digital mammography, visit RadiologyInfo.org.
Linda Brooks | EurekAlert!
Bern’s surgical procedure for brain tumours a world leader
03.11.2015 | Universitätsspital Bern
Siemens Healthcare introduces first Twin Robotic X-Ray system
29.10.2015 | Siemens AG
Chemical weathering of rocks over geological time scales is an important control on the stability of the climate. This weathering is, in turn, highly dependent...
Before the fluid of the middle ear drains and sound waves penetrate for the first time, the inner ear cells of newborn rodents practice for their big debut. Researchers at Johns Hopkins report they have figured out the molecular chain of events that enables the cells to make “sounds” on their own, essentially “practicing” their ability to process sounds in the world around them.
The researchers, who describe their experiments in the Dec. 3 edition of the journal Cell, show how hair cells in the inner ear can be activated in the absence...
Planet Earth experienced a global climate shift in the late 1980s on an unprecedented scale, fuelled by anthropogenic warming and a volcanic eruption, according to new research published this week.
Scientists say that a major step change, or ‘regime shift’, in the Earth’s biophysical systems, from the upper atmosphere to the depths of the ocean and from...
The Fraunhofer Institute for Solar Energy Systems ISE has installed 70 photovoltaic modules on the outer façade of one of its lab buildings. The modules were...
Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.
In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid...
01.12.2015 | Event News
30.11.2015 | Event News
25.11.2015 | Event News
01.12.2015 | Earth Sciences
01.12.2015 | Life Sciences
01.12.2015 | Earth Sciences