What distinguishes the new device system is that it is has a main column intended to protect the aorta and exclude the aneurysm from blood flow and two offshoot devices intended to protect the two renal arteries. The device is not commercially available in the United States, and will only be available at selected clinical study sites for investigational use.
Courtesy of Endologix Inc
The Ventana stent graft system
"These devices could allow management of aortic aneurysms that extend up to and may involve the renal arteries," said Methodist DeBakey Heart & Vascular Center Medical Director Alan Lumsden, M.D., who is leading the trial at Methodist. "They permit branches to be inserted through the main device and into the renal arteries in order to maintain blood flow to the kidneys. This has not been part of currently available devices. The device is meant to address the needs of patients whose aortic aneurysms are more extensive."
Stent grafts are light, metal-frame cylinders surrounded by a cloth-like covering. Similar devices are used to strengthen and protect blood vessels that have developed aneurysms -- weakened to the point that rupture, or dissection, is possible. An aneurysm is a weakening or ballooning in a blood vessel wall.
The aorta extends up and out of the heart and down to the lower back. Abdominal aortic aneurysm (AAA) is a weakening of the lower half of the aorta. That weakening may cause the aorta to bow outward, as if swollen, or even to develop a bubble. If the aneurysm dissects, blood spills into the body. The lost blood supply to the brain and other important organs is usually deadly.
The Ventana stent graft system received an investigational device exemption (IDE) conditional approval from the United States Food and Drug Administration recently for the purpose of evaluating its safety and feasibility in treating certain types of abdominal aortic aneurysms that are near to or may involve the renal arteries. In November, Methodist will be the procedural training site for medical researchers participating in the national feasibility study. A pivotal trial will also be conducted at these and additional research sites.
Many patients have aneurysms that extend from the aorta into one or both of the arteries that lead to the kidneys, organs that help the body remove toxins and that help regulate blood pressure. Keeping those aneurysms from rupturing is of great concern, Lumsden says.
"The open repair of aneurysms involving the renal arteries is called a juxtarenal, pararenal, or thoracoabdominal aneurysm repair," Lumsden said. "This has involved opening both the chest and abdomen at the same time and represents one of the largest procedures we ever perform. Many patients are just not able to tolerate the operation. In those who undergo surgery the complication rate is high and the recovery very difficult. We're hopeful this new device will permit an endovascular treatment to be extended to a much bigger group of patients."
Lumsden is also chair of Methodist's Department of Cardiovascular Surgery, a professor of cardiothoracic surgery in the Cornell University Weill Cornell Medical College, and a fellow of the American College of Surgeons.
Endologix Inc. develops and manufactures minimally invasive treatments for aortic disorders. Additional information about the company can be found at http://www.endologix.com.
Journalists interested in speaking with Dr. Lumsden should contact David Bricker, The Methodist Hospital, at 832-667-5811 or firstname.lastname@example.org
David Bricker | Newswise Science News
Visualizing gene expression with MRI
23.12.2016 | California Institute of Technology
Illuminating cancer: Researchers invent a pH threshold sensor to improve cancer surgery
21.12.2016 | UT Southwestern Medical Center
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences