Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers use CT to predict heart disease

28.09.2010
Using incidental findings from routine diagnostic CT, radiologists may be better able to identify people at high risk for cardiovascular disease, according to a new study appearing online and in the November issue of Radiology.

"The results of this study show that radiologists can predict cardiovascular disease fairly well using incidental findings of calcifications of the aortic wall on CT, along with minimal patient information, such as age, gender and the reason for the CT," said the study's lead author, Martijn J. A. Gondrie, M.D., from the Julius Center for Health Sciences and Primary Care at the University Medical Center Utrecht in the Netherlands. "Ultimately, this easily executed extra risk stratification has the potential to reduce future heart attacks or other cardiovascular events."

Over the past 10 years, the use of chest CT has increased substantially, and CT image quality has dramatically improved. As a result, many more incidental findings occur. Incidental findings are unexpectedly detected imaging characteristics that are unrelated to the original clinical indication for the CT.

Dr. Gondrie's study is part of the Prognostic Value of Ancillary Information in Diagnostic Imaging (PROVIDI) project, which aims to investigate the relevance of unexpectedly detected imaging findings on chest CT.

"This is the first study to investigate whether incidental findings can predict future disease in a routine care setting," Dr. Gondrie said. "Incidental findings are obtained without additional radiation exposure or cost to the patient and may hold valuable clues as to the patient's overall health and their risk for future disease."

Dr. Gondrie and colleagues developed prediction models incorporating incidental aortic findings detected on chest CT. From a total of 6,975 patients who had undergone diagnostic, contrast-enhanced chest CT for non-cardiovascular indications, a representative sample of 817 patients, plus 347 patients who experienced a cardiovascular event during a mean follow-up period of 17 months, were included in the study. Scores were assigned for incidental aortic abnormalities found on CT, including calcifications, plaques, elongation and other irregularities. Other factors taken into account included the patient's age, gender, and CT indication.

While each aortic abnormality was highly predictive, the prediction model incorporating the sum score for aortic calcifications was most indicative of future cardiovascular events.

"PROVIDI is the first study of its scale and scope that seeks to investigate the potential of incidental findings to predict future disease and thus identify patients at risk," Dr. Gondrie said. "It generates the much-needed insights that allow more effective utilization of the increasing amount of diagnostic information, and it could potentially change the way radiologists contribute to the efficiency of daily patient care."

"Cardiovascular Disease: Prediction with Ancillary Aortic Findings on chest CT Scans in Routine Practice." Collaborating with Dr. Gondrie were Willem P. T. M. Mali, M.D., Ph.D., Peter C. Jacobs, M.D., Ph.D., Ay L. Oen, M.D., and Yolanda van der Graaf, M.D., Ph.D., for the PROVIDI Study Group.

Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc. (http://radiology.rsna.org/)

RSNA is an association of more than 44,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (RSNA.org)

For patient-friendly information on chest CT, visit RadiologyInfo.org.

Linda Brooks | EurekAlert!
Further information:
http://www.rsna.org

More articles from Medical Engineering:

nachricht Biocompatible 3-D tracking system has potential to improve robot-assisted surgery
17.02.2017 | Children's National Health System

nachricht Real-time MRI analysis powered by supercomputers
17.02.2017 | University of Texas at Austin, Texas Advanced Computing Center

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Biocompatible 3-D tracking system has potential to improve robot-assisted surgery

17.02.2017 | Medical Engineering

Real-time MRI analysis powered by supercomputers

17.02.2017 | Medical Engineering

Antibiotic effective against drug-resistant bacteria in pediatric skin infections

17.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>