Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New ‘chemically-sensitive MRI scan’ may bypass some invasive diagnostic tests in next decade

20.08.2007
A new chemical compound which could remove the need for patients to undergo certain invasive diagnostic tests in the future has been created by scientists at Durham University.

Research published in the academic journal, Chemical Communications, reveals that this new compound could be used in a ‘chemically-sensitive MRI scan’ to help identify the extent of progression of diseases such as cancer, without the need for intrusive biopsies.

The researchers, who are part of an Engineering and Physical Sciences Research Council (EPSRC) funded group developing new ways of imaging cancer, have created a chemical which contains fluorine. It could, in theory, be given to the patient by injection before an MRI scan. The fluorine responds differently according to the varying acidity in the body, so that tumours could be highlighted and appear in contrast or ‘light up’ on the resulting scan.

Professor David Parker of Durham University’s Department of Chemistry explained: “There is very little fluorine present naturally in the body so the signal from our compound stands out. When it is introduced in this form it acts differently depending on the acidity levels in a certain area, offering the potential to locate and highlight cancerous tissue.”

Professor Parker’s team is the first to design a version of a compound containing fluorine which enables measurements to be taken quickly enough and to be read at the right ‘frequency’ to have the potential to be used with existing MRI scanners, whilst being used at sufficiently low doses to be harmless to the patient.

Professor Parker continued: “We have taken an important first step towards the development of a selective new imaging method. However, we appreciate that there is a lot of work to do to take this laboratory work and put it into practice. In principle, this approach could be of considerable benefit in the diagnosis of diseases such as breast, liver or prostate cancer.”

Durham University has filed a patent on this new approach and is looking for commercial partners to help develop the research. Professor Parker and his team believe that molecules containing fluorine could be used in mainstream MRI diagnoses within the next decade.

Chris Hiley, Head of Policy and Research Management at The Prostate Cancer Charity, said: “This is interesting work. The researchers are still some way from testing how this new idea might work in people but they are dealing with a knotty and important problem. In prostate cancer in particular more research is needed into cancer imaging as current techniques need improving.

“This development could have applications in many other cancers too. Once transferred from the lab to the bedside this research has potential to help show exactly where cancer may be in the body. This would add certainty to treatment decisions and improve monitoring of cancer progress. Looking even further into the future it could even have some use in improving diagnosis.”

Media and Public Affairs Team | alfa
Further information:
http://www.durham.ac.uk
http://www.rsc.org/Publishing/Journals/CC/article.asp?doi=b705844f

More articles from Medical Engineering:

nachricht Novel PET tracer identifies most bacterial infections
06.10.2017 | Society of Nuclear Medicine and Molecular Imaging

nachricht Teleoperating robots with virtual reality
05.10.2017 | Massachusetts Institute of Technology, CSAIL

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Osaka university researchers make the slipperiest surfaces adhesive

18.10.2017 | Materials Sciences

Space radiation won't stop NASA's human exploration

18.10.2017 | Physics and Astronomy

Los Alamos researchers and supercomputers help interpret the latest LIGO findings

18.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>