Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New imaging techniques avoid unnecessary diagnostic tests for Klippel-Trénaunay vascular malformation

07.05.2007
The use of multislice computed tomography (CT) - a latest generation scanner – or of magnetic resonance (MR) in the diagnosis of a vascular malformation of congenital origin – a syndrome known as Klippel-Trénaunay, can avoid patients being subjected to a series of tests, saving time and providing more effective treatment.

The reason for these advantages lies in the fact that both imaging techniques enable an overall evaluation of the Klippel-Trénaunay syndrome. More specifically, the administration of an intravenous contrast agent (angio-CT, angio-MR) enables the diagnosis and efficient determination of the origin and extent of the congenital vascular malformation typical of this syndrome. All this is outlined in an article by specialists at the University Hospital of the University of Navarre, recently published in the internationally-renowned journal specialising in dermatology, the Journal of the American Academy of Dermatology.

Doctor Pedro Redondo Bellón, member of the Department of Dermatology at ther Navarre university clinic and Doctor Gorka Bastarrika Alemañ from the Department of Radiology, describe the Klippel-Trénaunay syndrome as a vascular malformation that affects the limbs and manifests itself in the form of a “port wine” stain. It is caused by a series of large dilations of (blood) vessels which form a complex knotted ball. The syndrome causes an increase in the size of the limb at the expense of bone and soft tissues. Incidence is one in every 30,000 newborn babies.

Avoiding tests and saving time

To analyse the extent of the ailment and draw up the diagnosis, in collaboration with the Radiology service, two non-intrusive techniques have been applied in a novel manner - the angio-CT y and the angio-MR, which, to date, have not been used to these ends.

By means of the two radiological procedures, the patient being subjected to a battery of tests is avoided – the ecography, the magnetic resonance, simple radiographies and conventional angiographies (intrusive studies of arteriography or flebography). Now, with just one test, an overall visualisation of the affected limb can be effected. The angio-CT or the angio-MR provide the doctor with information on the size of the limb as well as showing the vascular anomalies of the patient (the connections between the vessels and the existence or otherwise of a deep venous system, amongst other fundamental aspects) in order to evaluate the illness.

For the exploration of Klippel-Trénaunay syndrome, the angio-CT is initially used, except with paediatric patients, where the use of angio-MR is recommended due to its lack of radiation. The end-result information provided by both diagnostic techniques is similar and so it is probable that, in the near future and with advances in MR, this technique will also be used with adults.

Treatment with microfoam

The reference treatment used with patients suffering from Klippel-Trénaunay syndrome at the University Hospital of the University of Navarre involves the injection of polydocanol microfoam, a novel procedure applied in a general way for treating varicose veins and, more specifically, for certain vascular malformations.

This treatment, also known as flebosclerosis with microfoam, enables the elimination of anomalous veins of practically all calibres – while avoiding surgery. This study of the administration of treatment with microfoam in patients with Klippel-Trénaunay syndrome is subsidised by the Government of Navarre. It should also be pointed out that, for five years now, University Hospital has been using sclerotherapy with persons affected by vascular malformations.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&Berri_Kod=1300&hizk=I

More articles from Medical Engineering:

nachricht MRI technique differentiates benign breast lesions from malignancies
20.02.2018 | Radiological Society of North America

nachricht True to type: From human biopsy to complex gut physiology on a chip
14.02.2018 | Wyss Institute for Biologically Inspired Engineering at Harvard

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

'Lipid asymmetry' plays key role in activating immune cells

20.02.2018 | Life Sciences

MRI technique differentiates benign breast lesions from malignancies

20.02.2018 | Medical Engineering

Major discovery in controlling quantum states of single atoms

20.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>