Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New imaging techniques avoid unnecessary diagnostic tests for Klippel-Trénaunay vascular malformation

07.05.2007
The use of multislice computed tomography (CT) - a latest generation scanner – or of magnetic resonance (MR) in the diagnosis of a vascular malformation of congenital origin – a syndrome known as Klippel-Trénaunay, can avoid patients being subjected to a series of tests, saving time and providing more effective treatment.

The reason for these advantages lies in the fact that both imaging techniques enable an overall evaluation of the Klippel-Trénaunay syndrome. More specifically, the administration of an intravenous contrast agent (angio-CT, angio-MR) enables the diagnosis and efficient determination of the origin and extent of the congenital vascular malformation typical of this syndrome. All this is outlined in an article by specialists at the University Hospital of the University of Navarre, recently published in the internationally-renowned journal specialising in dermatology, the Journal of the American Academy of Dermatology.

Doctor Pedro Redondo Bellón, member of the Department of Dermatology at ther Navarre university clinic and Doctor Gorka Bastarrika Alemañ from the Department of Radiology, describe the Klippel-Trénaunay syndrome as a vascular malformation that affects the limbs and manifests itself in the form of a “port wine” stain. It is caused by a series of large dilations of (blood) vessels which form a complex knotted ball. The syndrome causes an increase in the size of the limb at the expense of bone and soft tissues. Incidence is one in every 30,000 newborn babies.

Avoiding tests and saving time

To analyse the extent of the ailment and draw up the diagnosis, in collaboration with the Radiology service, two non-intrusive techniques have been applied in a novel manner - the angio-CT y and the angio-MR, which, to date, have not been used to these ends.

By means of the two radiological procedures, the patient being subjected to a battery of tests is avoided – the ecography, the magnetic resonance, simple radiographies and conventional angiographies (intrusive studies of arteriography or flebography). Now, with just one test, an overall visualisation of the affected limb can be effected. The angio-CT or the angio-MR provide the doctor with information on the size of the limb as well as showing the vascular anomalies of the patient (the connections between the vessels and the existence or otherwise of a deep venous system, amongst other fundamental aspects) in order to evaluate the illness.

For the exploration of Klippel-Trénaunay syndrome, the angio-CT is initially used, except with paediatric patients, where the use of angio-MR is recommended due to its lack of radiation. The end-result information provided by both diagnostic techniques is similar and so it is probable that, in the near future and with advances in MR, this technique will also be used with adults.

Treatment with microfoam

The reference treatment used with patients suffering from Klippel-Trénaunay syndrome at the University Hospital of the University of Navarre involves the injection of polydocanol microfoam, a novel procedure applied in a general way for treating varicose veins and, more specifically, for certain vascular malformations.

This treatment, also known as flebosclerosis with microfoam, enables the elimination of anomalous veins of practically all calibres – while avoiding surgery. This study of the administration of treatment with microfoam in patients with Klippel-Trénaunay syndrome is subsidised by the Government of Navarre. It should also be pointed out that, for five years now, University Hospital has been using sclerotherapy with persons affected by vascular malformations.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&Berri_Kod=1300&hizk=I

More articles from Medical Engineering:

nachricht A Challenging European Research Project to Develop New Tiny Microscopes
28.03.2017 | Technische Universität Braunschweig

nachricht 3-D visualization of the pancreas -- new tool in diabetes research
15.03.2017 | Umea University

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Transport of molecular motors into cilia

28.03.2017 | Life Sciences

A novel hybrid UAV that may change the way people operate drones

28.03.2017 | Information Technology

NASA spacecraft investigate clues in radiation belts

28.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>