Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


MR angiography highly accurate in detecting blocked arteries

A novel type of contrast-enhanced magnetic resonance (MR) angiography is highly accurate in identifying blockages in the arteries that carry blood to the brain, according to a study in the February issue of Radiology.

"Contrast-enhanced MR angiography provided highly accurate information about the supra-aortic arteries," said Kambiz Nael, M.D., research fellow and radiology resident at the David Geffen School of Medicine at UCLA in Los Angeles. "MR angiography produced results comparable to the gold standard of digital subtraction angiography (DSA) and multidetector computed tomography (CT) angiography. In addition, this technology produced images with higher resolution over a larger field of view in a shorter amount of time than previous contrast-enhanced MR angiography techniques," he said.

Arterial occlusive disease consists of narrowed or blocked arteries. It commonly affects the supra-aortic arteries, which supply blood to the brain, and is a leading cause of stroke. Currently DSA is the reference standard for evaluating these arteries. However, in 2.5 percent of cases DSA can cause a mini-stroke, and, in rare instances, permanent neurological damage. Therefore, CT and MR angiography are increasingly being used to diagnose arterial occlusive disease. As technology has improved, MR angiography offers advantages over CT, particularly because it delivers no ionizing radiation to the patient.

"MR angiography, using a small quantity of MRI dye injected into a vein in the arm, can produce detailed images of the arteries supplying the brain and can detect even minor degrees of narrowing or blockage. It does not involve exposure to x-rays and is widely regarded as a very safe, painless test," Dr. Nael said.

The researchers studied 80 patients (44 men and 36 women) with suspected arterial occlusive disease to compare the performance of contrast-enhanced MR angiography to DSA and CT angiography. Two independent readers evaluated the images. Blockages were detected with MR angiography in 208 (reader 1) and 218 (reader 2) segments of artery, which correlated significantly to the DSA and CT findings. In addition, MR angiography proved highly accurate (94 to 100 percent) for detecting blockages of over 50 percent, and image quality was rated sufficient to excellent for 97 percent of the arterial segments evaluated.

"This procedure should be highly cost effective for clinical use, because of the speed and modest dose of contrast required," Dr. Nael said. "In the absence of contraindications to MRI, I would recommend MR angiography over DSA and CTA for routine use—avoiding increased risk of mini-stroke and radiation exposure."

Dr. Nael predicts that in most cases, contrast-enhanced MR angiography could replace other diagnostic techniques for evaluation of all the arteries that supply blood to the brain.

"As the technology evolves, MR angiography will likely become even faster and more powerful," he said.

Maureen Morley | EurekAlert!
Further information:

More articles from Medical Engineering:

nachricht Gentle sensors for diagnosing brain disorders
29.09.2016 | King Abdullah University of Science and Technology

nachricht New imaging technique in Alzheimer’s disease - opens up possibilities for new drug development
28.09.2016 | Lund University

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Oasis of life in the ice-covered central Arctic

24.10.2016 | Earth Sciences

‘Farming’ bacteria to boost growth in the oceans

24.10.2016 | Life Sciences

Light-driven atomic rotations excite magnetic waves

24.10.2016 | Physics and Astronomy

More VideoLinks >>>