The devices are a Bruker BIOSPEC 70/30 spectrometer with a horizontal magnet, making it possible to carry out magnetic resonance spectroscopy imaging in vivo on animals (from mice to rabbits), and an NMR Bruker AvanceII 600 spectrometer combined with a high-resolution liquid chromatography team and a mass spectrometer. Both pieces of equipment will have various applications, especially in the field of biomedical research. In total, the UAB has invested €3 million in the equipment purchased and the work carried out to make room for it.
The BIOSPEC 70/30 spectrometer and the AvanceII 600 LC-NMR/MS cost approximately €1.5 million and €900,000 respectively, and were funded between the European Regional Development Fund (ERDF, project UNAB05-33-008), the Spanish Ministry of Education and Science (PCT-020400-2005-19 and PCT-010000-2006-14), the Catalan Government and the University itself. The facilities needed to be enlarged to accommodate the new equipment, and this was funded entirely by the UAB. The work is expected to be completed by May 2007, with the equipment being installed in June.
The BIOSPEC 70/30 is very similar to magnetic resonance equipment used for clinical purposes, and makes it possible to carry out magnetic resonance imaging and spectroscopy on small animals. This will be the first equipment of its kind in Catalonia and the third in Spain. The equipment at the UAB will include an ultra-shielded and refrigerated superconducting magnet with a 30cm bore diameter and new-generation electronics with more powerful amplifiers, steeper gradients and double synthesising waves. The BIOSPEC 70/30 will be set up for a wide variety of experiments for the detection of different nuclei, and will make it possible to obtain high-resolution and high-quality images. Because of the equipment's sensitivity, it will be set up inside a Faraday cage to protect it from external electromagnetic interference.
The AvanceII 600 LC-NMR/MS is aimed more towards basic research. It will be the first equipment in Spain to combine integrally magnetic resonance techniques, liquid chromatography and mass spectrometry. It will include an ultra-shielded and superconducting 14-tesla magnet and new-generation electronics. The liquid chromatograph to which it will be joined will separate the samples into different fractions, and these will then be analysed using a mass spectrometer and the NMR spectrometer.
This easy-to-upgrade equipment has many applications and will be very useful for biomedical research. The BIOSPEC 70/30 will, for example, enable researchers to advance their research into cancer, neurological diseases, diabetes, and other metabolic conditions and disorders through MR studies on animal models. Obviously it will also be possible to study plants used in agrigenomics. Furthermore, the AvanceII 600 LC-NMR/MS spectrometer will make it possible to work with libraries of compounds for pharmacological applications and to analyse liquid samples in the field of proteomics and metabonomics (analysing changes in the metabolism of animals to diagnose diseases earlier and more accurately), as well as food samples.
Since it was opened in 1982, the SeRMN has served the UAB research community and any external users from other research institutions and businesses.
Octavi López Coronado | alfa
'Memtransistor' brings world closer to brain-like computing
22.02.2018 | Northwestern University
MRI technique differentiates benign breast lesions from malignancies
20.02.2018 | Radiological Society of North America
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy