Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Leading European experts in magnetic resonance for animals

12.01.2007
The UAB SeRMN is enlarging its facilities to make room for two new cutting-edge machines for nuclear magnetic resonance (NMR).

The devices are a Bruker BIOSPEC 70/30 spectrometer with a horizontal magnet, making it possible to carry out magnetic resonance spectroscopy imaging in vivo on animals (from mice to rabbits), and an NMR Bruker AvanceII 600 spectrometer combined with a high-resolution liquid chromatography team and a mass spectrometer. Both pieces of equipment will have various applications, especially in the field of biomedical research. In total, the UAB has invested €3 million in the equipment purchased and the work carried out to make room for it.

The BIOSPEC 70/30 spectrometer and the AvanceII 600 LC-NMR/MS cost approximately €1.5 million and €900,000 respectively, and were funded between the European Regional Development Fund (ERDF, project UNAB05-33-008), the Spanish Ministry of Education and Science (PCT-020400-2005-19 and PCT-010000-2006-14), the Catalan Government and the University itself. The facilities needed to be enlarged to accommodate the new equipment, and this was funded entirely by the UAB. The work is expected to be completed by May 2007, with the equipment being installed in June.

The BIOSPEC 70/30 is very similar to magnetic resonance equipment used for clinical purposes, and makes it possible to carry out magnetic resonance imaging and spectroscopy on small animals. This will be the first equipment of its kind in Catalonia and the third in Spain. The equipment at the UAB will include an ultra-shielded and refrigerated superconducting magnet with a 30cm bore diameter and new-generation electronics with more powerful amplifiers, steeper gradients and double synthesising waves. The BIOSPEC 70/30 will be set up for a wide variety of experiments for the detection of different nuclei, and will make it possible to obtain high-resolution and high-quality images. Because of the equipment's sensitivity, it will be set up inside a Faraday cage to protect it from external electromagnetic interference.

The AvanceII 600 LC-NMR/MS is aimed more towards basic research. It will be the first equipment in Spain to combine integrally magnetic resonance techniques, liquid chromatography and mass spectrometry. It will include an ultra-shielded and superconducting 14-tesla magnet and new-generation electronics. The liquid chromatograph to which it will be joined will separate the samples into different fractions, and these will then be analysed using a mass spectrometer and the NMR spectrometer.

This easy-to-upgrade equipment has many applications and will be very useful for biomedical research. The BIOSPEC 70/30 will, for example, enable researchers to advance their research into cancer, neurological diseases, diabetes, and other metabolic conditions and disorders through MR studies on animal models. Obviously it will also be possible to study plants used in agrigenomics. Furthermore, the AvanceII 600 LC-NMR/MS spectrometer will make it possible to work with libraries of compounds for pharmacological applications and to analyse liquid samples in the field of proteomics and metabonomics (analysing changes in the metabolism of animals to diagnose diseases earlier and more accurately), as well as food samples.

Since it was opened in 1982, the SeRMN has served the UAB research community and any external users from other research institutions and businesses.

Octavi López Coronado | alfa
Further information:
http://www.uab.es

More articles from Medical Engineering:

nachricht PET identifies which prostate cancer patients can benefit from salvage radiation treatment
05.12.2017 | Society of Nuclear Medicine and Molecular Imaging

nachricht Designing a golden nanopill
01.12.2017 | University of Texas at Austin, Texas Advanced Computing Center

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Long-lived storage of a photonic qubit for worldwide teleportation

12.12.2017 | Physics and Astronomy

Multi-year submarine-canyon study challenges textbook theories about turbidity currents

12.12.2017 | Earth Sciences

Electromagnetic water cloak eliminates drag and wake

12.12.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>