Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Scientists engineer human tissue with electricity

23.06.2006
Scientists at The University of Manchester have developed a new technique which uses electricity to engineer human tissue. They now believe it may have the potential to engineer bespoke bone marrow.

The technique, which uses electric fields to build up layers of cells to form a tissue, is being used to create Hematons – aggregates of blood producing cells essential in the function of healthy bone marrow.

Dr Gerard Markx, of the School of Chemical Engineering and Analytical Science, has developed the technique based on a phenomenon called dielectrophoresis.

Dr Markx said: “We have proven this technique works, and have created some very simple Hematon structures in the lab. If we can perfect this technique then it may one day be possible to create artificial bone marrow outside the body and produce any given blood type.”

Dr Markx and his research team, which includes scientists in the University’s Faculty of Life Sciences, have so far created tissue 200 microns thick using the technique.

The function of bone marrow in the body is the production of blood. The most productive part of the bone marrow is formed by the hematon. Hematons are thought to be dysfunctional in patients suffering from bone marrow diseases like leukaemia.

Tissue is made using a series of glass slides with micro-electrodes etched on top of them. A solution containing cells is introduced to the slides. Electric fields are then created between the electrodes by running a small AC current through them.

In a similar way to which iron filings are attracted to the poles of magnets, the cells are attracted to the regions between the electrodes. As the cells collect together layers of cells build up, forming tissue.

Dr Markx said: “The use of electricity enables greater control over the position of the cells than conventional techniques. By varying the voltage and using different electrode shapes, cells can be positioned and stacked on top of each other in any pattern. Different electric fields can also be used to attract different types of cells. Most importantly, cells can be kept alive and active.”

The micro-electrodes used measure between 50-250 microns in size and can be positioned in any formation.

Simon Hunter | alfa
Further information:
http://www.manchester.ac.uk

More articles from Medical Engineering:

nachricht Novel PET tracer identifies most bacterial infections
06.10.2017 | Society of Nuclear Medicine and Molecular Imaging

nachricht Teleoperating robots with virtual reality
05.10.2017 | Massachusetts Institute of Technology, CSAIL

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Osaka university researchers make the slipperiest surfaces adhesive

18.10.2017 | Materials Sciences

Space radiation won't stop NASA's human exploration

18.10.2017 | Physics and Astronomy

Los Alamos researchers and supercomputers help interpret the latest LIGO findings

18.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>