3D MRI can detect pancreatic cancer when it is smaller and patients have a greater likelihood of survival, a new study shows.
The study included 57 patients who had clinical symptoms of pancreatic cancer. All had contrast enhanced 3D gradient-echo MRI examinations. Radiologists correctly identified pancreatic cancer in 24 patients, said Richard Semelka, MD, professor of radiology, at the University of North Carolina, Chapel Hill, and an author of the study. Eight of the cancers found were less than two centimeters in size, Dr. Semelka said. “Currently patients with pancreatic cancer are treated with complete surgical resection and the smaller the tumor, the easier it is to remove,” he said.
Pancreatic cancer is usually diagnosed too late, said Dr. Semelka. About 40,000 people are diagnosed with the disease in the U.S. each year, and nearly all of them die. Pancreatic cancer is the fourth most common cause of cancer death in the U.S. “The symptoms of the disease are somewhat nonspecific and can easily be misinterpreted. In addition, the disease is very aggressive so if the disease is missed or the diagnosis is delayed, the patient’s chance for survival is dismal,” he said.
3D MRI did indicate pancreatic cancer in three patients, but biopsy showed they did not have the disease. However, one did have a neuroendocrine tumor and one had focal pancreatitis. Three patients were lost to follow-up, said Dr. Semelka. “No patient with a study interpreted as normal was subsequently found to have pancreatic cancer,” he added.
“We are now working with our internists to detect this disease earlier,” said Dr. Semelka. “We are encouraging them to refer their patients for a 3D MRI examination if a patient has severe mid-abdominal pain not explained by a back problem, sudden development of diabetes and/or sudden development of jaundice. Radiologists who are reading 3D MR images of patients with abdominal pain should also look for pancreatic cancer even if the patient didn’t have the examination for that purpose,” he said.
The study appears in the September 2005 issue of the American Journal of Roentgenology.
Keri Sperry | EurekAlert!
A Challenging European Research Project to Develop New Tiny Microscopes
28.03.2017 | Technische Universität Braunschweig
3-D visualization of the pancreas -- new tool in diabetes research
15.03.2017 | Umea University
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
28.03.2017 | Life Sciences
28.03.2017 | Information Technology
28.03.2017 | Physics and Astronomy