"Recently, there have been reports in the press focusing on the potential radiation risk from mammography, particularly as used for periodic screening," said the study's lead author, Martin J. Yaffe, Ph.D., senior scientist in imaging research at Sunnybrook Health Sciences Centre, and professor in the departments of medical biophysics and medical imaging at the University of Toronto. "Our study shows that the risk of cancer associated with routine screening in women age 40 and over is very low, especially when compared to the benefits associated with early detection."
Dr. Yaffe and his colleague, James G. Mainprize, Ph.D., developed a model for estimating the risk of radiation-induced breast cancer following exposure of the breast to ionizing radiation from various screening mammography scenarios and estimated the potential number of breast cancers, fatal breast cancers, and years of life lost attributable to mammography screening.
Using a radiation dose estimate of 3.7 milligrays (mGy), which is typical for digital mammography, and a cohort of 100,000 women, the researchers applied the risk model to predict the number of radiation-induced breast cancers attributable to a single examination and then extended the model to various screening scenarios beginning and ending at different ages.
The results showed that in 100,000 women, each receiving a dose of 3.7 mGy to both breasts, annual screening from age 40 to 55 years and biennial screening thereafter to age 74 years would result in 86 radiation-induced cancers, including 11 fatal cancers, and 136 life years lost.
Conversely, for the same cohort it was estimated that 497 lives and 10,670 life years would be saved by earlier detection.
"The predicted risk of radiation-induced breast cancer from mammography screening is low in terms of the numbers of cancers induced, the number of potential deaths, and the number of years of life lost," Dr. Yaffe said. "For women over 40, the expected benefits afforded by routine screening in terms of lives saved or years of life saved greatly exceeds this risk. For these women, radiation risk should not be a deterrent from screening."
"Risk of Radiation-induced Breast Cancer from Mammographic Screening."
Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc. (http://radiology.rsna.org/)
RSNA is an association of more than 46,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (RSNA.org)
For patient-friendly information on mammography, visit RadiologyInfo.org.
Linda Brooks | EurekAlert!
Water-filtered infrared-A (wIRA) overcomes swallowing disorders and hypersalivation – a case report
10.08.2017 | Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e.V.
New microscope technique reveals internal structure of live embryos
08.08.2017 | University of Illinois at Urbana-Champaign
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
17.08.2017 | Physics and Astronomy
17.08.2017 | Earth Sciences
17.08.2017 | Physics and Astronomy