"Although early-onset Alzheimer's dementia is quite rare, it can be devastating to the patients that carry the diagnosis," said Dr. Jacob Richard Hodge, lead researcher for this study at the Mayo Clinic in Rochester, Minn. "Symptoms are often unexpected and support networks are generally directed towards an older population."
In patients presenting with similar clinical severities of the disease, researchers for this study discovered a "cognitive reserve," which slowed the outward expression of symptoms. "Our research demonstrates that those patients with increasing education are better able to cope with the disease pathology before they express the symptoms of Alzheimer's dementia," Dr. Hodge said. This study evaluated PET-CT examinations in 91patients under age 65 to see if this cognitive reserve could be identified with early-onset AD, which often has a more aggressive course and progression.
Additionally, researchers replicated previously published data using PET-CT examinations, and they were able to detect significant abnormalities in patients with early-onset AD, thereby supporting its usefulness with younger patients. "Alzheimer's dementia is often not suspected in younger patients," Dr. Hodge said. "Therefore, PET-CT brain imaging can be helpful in the diagnosis."
While the discovery of the "cognitive reserve" will not slow the progression of the disease, Hodge is confident that patients can improve the quality of their lives with the proper diagnosis and education. "Once the diagnosis is determined, a patient can begin to manage the disease and plan for the future," Dr. Hodge stated.
Dr. Hodge will deliver a presentation on this study on Monday, May 2, 2011 at the 2011 ARRS Annual Meeting at the Hyatt Regency Chicago.
Keri Sperry | EurekAlert!
Novel PET tracer identifies most bacterial infections
06.10.2017 | Society of Nuclear Medicine and Molecular Imaging
Teleoperating robots with virtual reality
05.10.2017 | Massachusetts Institute of Technology, CSAIL
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
23.10.2017 | Physics and Astronomy
23.10.2017 | Earth Sciences
23.10.2017 | Health and Medicine