Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

NYU Langone offers vascular-targeted photodynamic therapy for localized prostate cancer

28.07.2010
NYU Langone Medical Center has begun a clinical trial offering vascular-targeted photodynamic therapy to patients with localized prostate cancer. This novel, minimally invasive procedure uses a light-activated drug to deliver light energy waves by way of laser fibers in order to destroy prostate cancer cells.

"This minimally invasive technique for localized prostate cancer offers the potential to destroy the cancer without making any incision or causing any potentially devastating sexual, urinary or reproductive side-effects," said Samir S. Taneja, MD, The James M. Neissa and Janet Riha Neissa Associate Professor of Urologic Oncology and director of the Division of Urologic Oncology at NYU Langone Medical Center and principal investigator for the national, multi-center clinical trial testing this technology. "This procedure only treats the cancerous part of the prostate gland, similar to how a lumpectomy might be done for breast cancer.

Photodynamic therapy is just one of the many personalized treatment options offered by the Smilow Comprehensive Prostate Cancer Center at NYU Langone Medical Center. The Center offers a wide range of the latest treatment options for prostate cancer including: open or robotic prostatectomy surgery, brachytherapy, external beam radiation therapy, cryotherapy and high-intensity focused ultrasound (HIFU), a focal therapy that uses high-energy sound waves to treat prostate cancer, now also in clinical trials at the medical center.

This Phase I/II photodynamic therapy trial is open to men diagnosed with localized prostate cancer -- determined by a needle biopsy and advanced imaging techniques -- who have chosen active surveillance, also known as "watchful-waiting. During the procedure, laser fibers are positioned over the prostate where cancer cells have been identified. Once in place, a photosensitizing drug called WST11 is administered to the patient intravenously and circulates throughout the blood stream for ten-minutes. The laser fibers are then activated to deliver a specific wavelength of light to the prostate for twenty-minutes. When the light comes into contact with the drug in circulation, the laser fibers destroy the blood vessels around the tumor shutting down the blood supply to the cancer. Patients are followed for a year after treatment with PSA tests after each visit and an MRI and needle biopsy performed at six months.

"Focal treatment of prostate cancer with techniques such as photodynamic therapy is an emerging paradigm since the over treatment of prostate cancer is a major concern for both physicians and patients," said Dr. Taneja who is also a member of the NYU Cancer Institute.

Recent European studies show photodynamic therapy successfully treats localized prostate cancer with minimal side effects. This study will investigate optimal dosage of the photosensitive drug and light-energy waves and measure outcomes of patients as well as long-term cancer control. Researchers believe the technology has the potential to treat any early stage prostate cancer as well as tumors in other organs of the body.

About NYU Langone Medical Center

NYU Langone Medical Center is one of the nation's premier centers of excellence in healthcare, biomedical research, and medical education. For over 170 years, NYU physicians and researchers have made countless contributions to the practice and science of health care. Today the Medical Center consists of NYU School of Medicine, including the Smilow Research Center, the Skirball Institute of Biomolecular Medicine, and the Sackler Institute of Graduate Biomedical Sciences; and the NYU Hospitals Center, including Tisch Hospital, a 705-bed acute-care general hospital, Rusk Institute of Rehabilitation Medicine, the first and largest facility of its kind, and NYU Hospital for Joint Diseases, a leader in musculoskeletal care, a Clinical Cancer Center and numerous ambulatory sites.

Lauren Woods | EurekAlert!
Further information:
http://www.nyumc.org

More articles from Medical Engineering:

nachricht Rutgers researchers develop automated robotic device for faster blood testing
14.06.2018 | Rutgers University

nachricht Speech comprehension with a cochlear implant
04.06.2018 | Universität zu Lübeck

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Temperature-controlled fiber-optic light source with liquid core

In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.

Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...

Im Focus: Overdosing on Calcium

Nano crystals impact stem cell fate during bone formation

Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Better model of water under extreme conditions could aid understanding of Earth's mantle

21.06.2018 | Earth Sciences

What are the effects of coral reef marine protected areas?

21.06.2018 | Life Sciences

The Janus head of the South Asian monsoon

21.06.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>