Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Newer techniques are making cardiac CT safer for children

18.07.2011
Coronary computed tomography angiography (CTA) has excellent image quality and diagnostic confidence for the entire spectrum of pediatric patients, with significant reduction of risk with recent technological advancements, according to a study to be presented at the Sixth Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography (SCCT) in Denver, July 14-17.

"Traditionally, pediatric patients who require coronary artery imaging have undergone a cardiac catheterization, which is an invasive procedure with a significant radiation dose, requiring sedation or anesthesia for all patients," explained B. Kelly Han, MD, a pediatric cardiologist at Minneapolis Heart Institute® at Abbott Northwestern Hospital and the Children's Heart Clinic and Children's Hospitals and Clinics in Minneapolis.

"The newer CT scanners deliver far less radiation than both previous generation CT scanners and catheter based angiography. Also, CTA is non-invasive and has different protocols that can be tailored to decrease the risk for each individual patient."

"One barrier to applying coronary CTA in children has been their relatively high heart rates. Using a combination of medication to slow the heart rate and the new scanner technology, we have been able to obtain excellent images of the coronary arteries in patients as young as five months of age" she said.

Han and colleagues conducted a retrospective review of all coronary CTAs performed on patients less than 18 years of age at Minneapolis Heart Institute® from June 2007 through February 2011. The researchers examined the heart rate control with beta blockade, and the radiation dose with the varied scan modes, with the goal of comparing the image quality and the radiation dose.

Patients were separated by scan mode into three groups:

Group One: First-generation, dual-source CT scanner with retrospective ECG gating (spiral scan mode);

Group Two: Second-generation, dual-source CT scanner with prospective ECG gating (sequential scan mode); and

Group Three: Second-generation, dual-source CT using prospective ECG gating with high pitch (flash-scan mode).

The researchers compared the age, heart rate, body surface area, radiation dose estimates and image quality between the three groups. They performed 76 scans in patients from three days to 18 years of age.

The differences in radiation dose between the three scan groups were statistically significant, according to the authors, and high image quality was maintained between groups despite the decreased radiation exposure, Han and colleagues reported. A high percentage of the patients had coronary artery pathology including anomaly, stenosis, or aneurysm. Overall, 17 patients underwent subsequent surgical intervention and surgical findings correlated with coronary CTA in all cases.

"We found that the newer imaging modes decrease the radiation dose between four-fold and seven-fold, without loss in diagnostic accuracy or image quality," Han said. "The estimated radiation dose reduction over traditional angiography is even greater. The aggressive use of beta-blockade to slow the heart rate, in combination with the newer scan modes allows for a very low radiation dose in this young patient population."

This technology also will "significantly decrease" the anesthesia and invasive access risk of coronary imaging, according to Han, as the images are acquired without having to access the heart, and all patients age seven or older did not require sedation.

Minneapolis Heart Institute®

The Minneapolis Heart Institute® is recognized internationally as one of the world's leading providers of heart and vascular care. This state-of-the-art facility combines the finest in personalized patient care with sophisticated technology in a unique, family-oriented environment. The Institute's programs, a number of which are conducted in conjunction with Abbott Northwestern Hospital, address the full range of heart and vascular health needs: prevention, diagnosis, treatment and rehabilitation.

Minneapolis Heart Institute Foundation

The Minneapolis Heart Institute Foundation (MHIF) is dedicated to creating a world without heart disease through groundbreaking clinical research and innovative education programs. MHIF's mission is to promote and improve cardiovascular health, quality of life and longevity for all.

Meghan Bethke | EurekAlert!
Further information:
http://www.mhif.org

Further reports about: CT scan CT scanner CTA ECG Heart heart rate radiation dose vascular health

More articles from Medical Engineering:

nachricht Novel chip-based gene expression tool analyzes RNA quickly and accurately
18.01.2018 | University of Illinois College of Engineering

nachricht Potentially life-saving health monitor technology designed by Sussex University physicists
10.01.2018 | University of Sussex

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>