The researchers discovery, which was published yesterday in the journal Nature Photonics, is that it is possible to distinguish aggregations of the proteins, believed to cause the diseases, from the the well-functioning proteins in the body by using multi-photon laser technique.
Structure of properly functioning protein (left) which is optically invisible to high power laser light, and toxic amyloid (right) responsible for brain diseases that might poten
Piotr Hanczyc, Chalmers University of Technology
“Nobody has talked about using only light to treat these diseases until now. This is a totally new approach and we believe that this might become a breakthrough in the research of diseases such as Alzheimer’s, Parkinson’s and Creutzfeldt-Jakob disease. We have found a totally new way of discovering these structures using just laser light”, says Piotr Hanczyc at Chalmers University of Technology.
If the protein aggregates are removed, the disease is in principle cured. The problem until now has been to detect and remove the aggregates.
The researchers now harbor high hopes that photo acoustic therapy, which is already used for tomography, may be used to remove the malfunctioning proteins. Today amyloid protein aggregates are treated with chemicals, both for detection as well as removal. These chemicals are highly toxic and harmful for those treated.
With multi photon laser the chemical treatment would be unnecessary. Nor would surgery be necessary for removing of aggregates. Due to this discovery it might, thus, be possible to remove the harmful protein without touching the surrounding tissue.
These diseases arise when amyloid beta protein are aggregated in large doses so they start to inhibit proper cellular processes.
Different proteins create different kinds of amyloids, but they generally have the same structure. This makes them different from the well-functioning proteins in the body, which can now be shown by multi photon laser technique.
Scientific article: Multiphoton absorption in amyloid protein fibresFor more information, please contact:
Bengt Nordén, Chalmers University of Technology, +46 730 34 64 41, firstname.lastname@example.org
Johanna Wilde, Press communicator, email@example.com, +46-31-772 20 29
http://www.nature.com/nphoton/journal/vaop/ncurrent/full/nphoton.2013.282.html Scientific articlehttp://www.mynewsdesk.com/uk/chalmers/images/properly-functioning-protein-and-amyloid-238841
Download high resolution image
MRI technique differentiates benign breast lesions from malignancies
20.02.2018 | Radiological Society of North America
True to type: From human biopsy to complex gut physiology on a chip
14.02.2018 | Wyss Institute for Biologically Inspired Engineering at Harvard
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
20.02.2018 | Life Sciences
20.02.2018 | Medical Engineering
20.02.2018 | Physics and Astronomy