The investigators will also design novel radiopharmaceuticals that will scan for gene activity of the disease and present the results in a realistic hologram-like display that can be touched and probed like genuine organs.
The two-year project is focused on the pancreas and pancreatic tumors, and has two aims: 1.) the molecular design of a single new imaging ligand for epidermal growth factor receptors, and 2.) the surgical simulation of human pancreatic cancer reconstructed from patient CT and PET scans.
Currently, the elements of surgery must be imagined by the surgeon from two-dimensional diagnostic images before an operation, according to Eric Wickstrom, Ph.D., professor of Biochemistry and Molecular Biology at Jefferson Medical College of Thomas Jefferson University. Three-dimensional holographic images will allow surgeons to see the lesion to be removed in the patient’s own anatomical environment and permit a “touch and feel” surgical strategy.
“This imaging system will provide a highly realistic environment in which to better understand an individual patient’s pathology, and to accurately plan and rehearse that patient’s operation,” said Wickstrom, the leader of the study. “This system will combine the 3D visual image with the sense of touch and permit surgeons to view, palpate and manipulate selected organs and tissues.”
“This state of the art procedure will significantly enhance our ability to evaluate new biomolecules for their eventual translation to improving surgical care of patients at Jefferson and beyond,” said Mathew Thakur, Ph.D., professor of Radiology and director of the Laboratories of Radiopharmaceutical Research and Molecular Imaging. Dr. Thakur is also part of the research team at Jefferson.
The Jefferson research team also includes Chang-Po Chen, Ph.D., from the department of Biochemistry and Molecular Biology; Devadhas Devakumar, Ph.D., from the department of Radiology; John Kairys, M.D., from the department of Surgery; and Martha Ankeny, M.Ed., director of Learning Resources. The Delaware team members include Karl Steiner, Ph.D., Kenneth Barner, Ph.D., and Rui Hu, all from the department of Electrical and Computer Engineering.
Emily Shafer | Newswise Science News
Further reports about: > 3D visual image > Biochemistry > CT and PET scans > Cancer > Delaware > Genetic clues > Molecular Biology > Molecular Target > PET scan > Radiopharmaceutical Research > Touch-and-Feel > genuine organs > human pancreatic cancer > radiology > surgical simulation > synthetic biology
UTSA study describes new minimally invasive device to treat cancer and other illnesses
02.12.2016 | University of Texas at San Antonio
Earlier Alzheimer's diagnosis may be possible with new imaging compound
02.11.2016 | Washington University School of Medicine
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.
Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
02.12.2016 | Medical Engineering
02.12.2016 | Agricultural and Forestry Science
02.12.2016 | Physics and Astronomy