The investigators will also design novel radiopharmaceuticals that will scan for gene activity of the disease and present the results in a realistic hologram-like display that can be touched and probed like genuine organs.
The two-year project is focused on the pancreas and pancreatic tumors, and has two aims: 1.) the molecular design of a single new imaging ligand for epidermal growth factor receptors, and 2.) the surgical simulation of human pancreatic cancer reconstructed from patient CT and PET scans.
Currently, the elements of surgery must be imagined by the surgeon from two-dimensional diagnostic images before an operation, according to Eric Wickstrom, Ph.D., professor of Biochemistry and Molecular Biology at Jefferson Medical College of Thomas Jefferson University. Three-dimensional holographic images will allow surgeons to see the lesion to be removed in the patient’s own anatomical environment and permit a “touch and feel” surgical strategy.
“This imaging system will provide a highly realistic environment in which to better understand an individual patient’s pathology, and to accurately plan and rehearse that patient’s operation,” said Wickstrom, the leader of the study. “This system will combine the 3D visual image with the sense of touch and permit surgeons to view, palpate and manipulate selected organs and tissues.”
“This state of the art procedure will significantly enhance our ability to evaluate new biomolecules for their eventual translation to improving surgical care of patients at Jefferson and beyond,” said Mathew Thakur, Ph.D., professor of Radiology and director of the Laboratories of Radiopharmaceutical Research and Molecular Imaging. Dr. Thakur is also part of the research team at Jefferson.
The Jefferson research team also includes Chang-Po Chen, Ph.D., from the department of Biochemistry and Molecular Biology; Devadhas Devakumar, Ph.D., from the department of Radiology; John Kairys, M.D., from the department of Surgery; and Martha Ankeny, M.Ed., director of Learning Resources. The Delaware team members include Karl Steiner, Ph.D., Kenneth Barner, Ph.D., and Rui Hu, all from the department of Electrical and Computer Engineering.
Emily Shafer | Newswise Science News
Further reports about: > 3D visual image > Biochemistry > CT and PET scans > Cancer > Delaware > Genetic clues > Molecular Biology > Molecular Target > PET scan > Radiopharmaceutical Research > Touch-and-Feel > genuine organs > human pancreatic cancer > radiology > surgical simulation > synthetic biology
Gentle sensors for diagnosing brain disorders
29.09.2016 | King Abdullah University of Science and Technology
New imaging technique in Alzheimer’s disease - opens up possibilities for new drug development
28.09.2016 | Lund University
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
25.10.2016 | Life Sciences
24.10.2016 | Earth Sciences
24.10.2016 | Life Sciences