Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Imaging Technique Could Help Physicians Ease the Aftermath of Breast Cancer

05.08.2010
Lasers Illuminate Women's Health in inaugural open-access journal Biomedical Optics Express

A new study of breast cancer survivors may help physicians ease a common side effect of cancer treatments. The collaborative research by Eva Sevick, Ph.D., Director of the Center for Molecular Imaging at the University of Texas Health Science Center in Houston (UTHSC), and Caroline Fife, M.D., Director of the Memorial Herman Wound Care Clinic at UTHSC, could bring relief to millions.

Their paper appears in the inaugural issue of Biomedical Optics Express, an online, open-access journal published by the Optical Society (OSA). The papers featured in the journal will encompass theoretical modeling and simulations, technology development, biomedical studies and clinical applications.

A substantial number of breast cancer survivors suffer from lymphedema in the aftermath of their cancer surgeries. In lymphedema, fluids accumulate in the arms, potentially causing disfiguring and debilitating swelling that can impact quality of life.

Treatments vary, but they generally consist of using manual and pneumatic therapies to "push" or stimulate the body to remove excess fluid and reduce tissue swelling. Finding out whether a treatment is working can take months. That's because the current method of assessing progress is to measure the circumference or volume of a limb and check for changes in swelling -- and a size change big enough to be measured takes time.

During this time, the condition might improve – or it might worsen.

The UTHSC research team has developed what promises to be a more sensitive and more immediate way to monitor the effectiveness of a treatment. Their new near-infrared fluorescence imaging technique examines the root cause of lymphedema: blockages or damages in the lymphatic system that prevent fluid from circulating through the body and cause it to pool in the limbs.

"The lymphatics are like the sewer system of your body," says Sevick. "If they get all plugged up, then there’s a flood."

Nine women – six with lymphedema and three controls – were injected with a near-infrared fluorescent dye that has been used safely for 50 years at much higher dosages. The dye is taken up by the lymphatic system. When tissue surfaces are exposed to a dim, near-infrared laser – harmless to the human body – the dye within fluoresces, revealing its transit through the lymphatic system.

"This is the only method that can directly check for improvements in lymphatic function in one sitting, before and after a treatment," says Sevick.

Physicians have several treatment options for controlling lymphedema. They may use compression bandages and massage limbs to manually encourage fluids to drain from the arm. Pneumatic compression devices, sleeves made of segmented chambers that inflate and squeeze, may provide a similar benefit at home, but they may not always be covered by Medicare reimbursements because of lacking direct evidence of their benefit.

"The problem is that there has been no good way to measure direct evidence of benefit," says Sevick. "Hopefully we can use near-infrared fluorescence imaging technique to show improved lymphatic function from these treatments."

The NIR fluorescence technique detected statistically significant improvements in fluid flow through the lymphatic system immediately after the use of pneumatic compression devices. A larger follow-up study will be needed to confirm the results of this pilot study, says Sevick.

The research was funded by the National Institutes of Health and by Tactile Systems Technology, Inc., which manufactures and markets the Flexitouch pneumatic compression devices tested in this research.

The paper "Direct evidence of lymphatic function improvement after advanced pneumatic compression device treatment of lymphedema" by Kristen E. Adams et al. can be accessed at: http://www.opticsinfobase.org/boe/abstract.cfm?uri=boe-1-1-114

About OSA

Uniting more than 106,000 professionals from 134 countries, the Optical Society (OSA) brings together the global optics community through its programs and initiatives. Since 1916 OSA has worked to advance the common interests of the field, providing educational resources to the scientists, engineers and business leaders who work in the field by promoting the science of light and the advanced technologies made possible by optics and photonics. OSA publications, events, technical groups and programs foster optics knowledge and scientific collaboration among all those with an interest in optics and photonics.

Lyndsay Basista | EurekAlert!
Further information:
http://www.osa.org

More articles from Medical Engineering:

nachricht Novel PET tracer identifies most bacterial infections
06.10.2017 | Society of Nuclear Medicine and Molecular Imaging

nachricht Teleoperating robots with virtual reality
05.10.2017 | Massachusetts Institute of Technology, CSAIL

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Electrode materials from the microwave oven

19.10.2017 | Materials Sciences

New material for digital memories of the future

19.10.2017 | Materials Sciences

Physics boosts artificial intelligence methods

19.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>