New EEG trace interpretation method predicts neurological recovery of cardiac arrest patients

Up until now, the use of electroencephalography (EEG) in the monitoring of cardiac patients has been limited due to interpretation difficulties.

A study conducted by a multi-disciplinary research team showed that variables derived from EEG traces can be used to predict neurological recovery even within the first 24 hours following cardiac arrest.

The researchers derived variables from the EEG trace which simplified the interpretation process. The long-term goal of the team is to develop methods that allow continuous monitoring of neurological recovery at hospitals. This would allow the health care personnel to promptly respond to changes in the patient’s brain status.

If blood circulation stops, the tissue in the patient’s body soon begins to suffer from reduced oxygen delivery. Brain cells are particularly sensitive to oxygen deprivation, which explains why even successfully resuscitated patients often sustain neurological damage. In its mildest form this is manifested as transient memory or movement disturbances; in the most serious cases, they can cause permanent unconsciousness.

Basically, an electroencephalogram (EEG) records the electrical activity of the brain in the same way as an electrocardiogram (ECG) records heart activity. Interpreting EEG traces is more difficult, however, since unlike the electrical activity of a regularly beating heart, the electrical activity of the brain consists of irregular impulses generated by billions of brain cells. While the applicability of EEG in predicting neurological recovery has long been known, difficulties in interpreting the recordings have limited the routine use of EEG in patient monitoring. Interpretation almost invariably requires consulting a specialist, which may cause a delay in treatment.

Miikka Ermes will publicly defend his doctoral thesis “Methods for the Classification of Biosignals Applied to the Detection of Epileptiform Waveforms and to the Recognition of Physical Activity” on Friday, 15 May 2009 starting at 12 noon. The public defence will take place in the Tietotalo Auditorium (room TB219) of the Tampere University of Technology (TUT), address: Korkeakoulunkatu 1, Tampere. Professor Georg Dorffner from the Medical University of Vienna (Austria) will act as the opponent.

The doctoral thesis, which belongs to the field of signal processing, is available on the Internet at
http://www.vtt.fi/inf/pdf/publications/2009/P707.pdf

For further information, please contact:

VTT Technical Research Centre of Finland
Miikka Ermes
Research Scientist
Tel. +358 40 530 9273
miikka.ermes@vtt.fi
Further information on VTT:
Senior Vice President
Olli Ernvall
Tel. +358 20 722 6747
olli.ernvall@vtt.fi
VTT Technical Research Centre of Finland is the biggest contract research organization in Northern Europe. VTT provides high-end technology solutions and innovation services. From its wide knowledge base, VTT can combine different technologies, create new innovations and a substantial range of world-class technologies and applied research services, thus improving its clients' competitiveness and competence. Through its international scientific and technology network, VTT can produce information, upgrade technology knowledge and create business intelligence and value added to its stakeholders.

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