Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Digital mammography reduces recall and biopsy rates

01.04.2014

Population-based screening with full-field digital mammography (FFDM) is associated with lower recall and biopsy rates than screen film mammography (SFM), suggesting that FFDM may reduce the number of diagnostic workups and biopsies that do not lead to diagnosis of breast cancer, according to a new study published online in the journal Radiology.

Previous population-based studies comparing the accuracy of SFM versus FFDM have reported conflicting results, and reported recall rates—or the rate at which women are called back for additional tests—have varied widely. In addition, past performance evaluations of breast imaging screening technologies do not account for the transition phase of adoption.

For this study, data collected from the Norwegian Breast Cancer Screening Program (NBCSP) was used to compare performance measures and outcomes before, during and after the transition from SFM to FFDM.

"The program invites women age 50 to 69 years to mammographic screening every two years," said Solveig Hofvind, Ph.D., from the Cancer Registry of Norway and Oslo University College, in Oslo, Norway. "We analyzed performance measures in the program as run in a usual setting."

To examine the effect of transition from SFM to FFDM, researchers analyzed the rate of cases, the recall rate, the rate of screen-detected cancer, and the rate of interval cancers.

"The study includes results from women screened with SFM only, with both SFM and FFDM, and with FFDM only. These combinations make us able to compare early performance measures achieved when using digital mammography in a routine setting, in a proper way," Dr. Hofvind said.

A total of 1,837,360 NBCSP screening exams were performed from 1996 through 2010, with 58.8 years being the average age at the time of screening. The overall recall rate was 3.4 percent for SFM and 2.9 percent for FFDM. The biopsy rate was 1.4 percent for SFM and 1.1 percent for FFDM.

Both the rate of invasive screening-detected and interval breast cancer remained stable during the transition from SFM to FFDM and after FFDM was firmly established. The positive predictive value of recalled examinations and of biopsy procedures increased from 19.3 percent and 48.3 percent to 22.7 percent and 57.5 percent, respectively, after adoption of FFDM.

By studying the transition phase of screening modality, researchers discovered FFDM implementation led to lower rates of false positive screening exams and fewer biopsies with benign outcome.

###

"Mammographic Performance in a Population-based Screening Program: Before, during, and after the Transition from Screen-Film to Full-Field Digital Mammography." Collaborating with Dr. Hofvind were Per Skaane, M.D., Ph.D., Joann G. Elmore, M.D., Ph.D., Sofie Sebuødegård, B.Sc., Solveig Roth Hoff, M.D., Ph.D., and Christoph I. Lee, M.D., MSHS.

Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc.

RSNA is an association of more than 53,000 radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)

For patient-friendly information on mammography, visit RadiologyInfo.org.

Linda Brooks | EurekAlert!

Further reports about: Cancer Digital RSNA Radiological Screening biopsy mammography technologies transition

More articles from Medical Engineering:

nachricht New technique makes brain scans better
22.06.2017 | Massachusetts Institute of Technology

nachricht New technology enables effective simultaneous testing for multiple blood-borne pathogens
13.06.2017 | Elsevier

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

Im Focus: Optoelectronic Inline Measurement – Accurate to the Nanometer

Germany counts high-precision manufacturing processes among its advantages as a location. It’s not just the aerospace and automotive industries that require almost waste-free, high-precision manufacturing to provide an efficient way of testing the shape and orientation tolerances of products. Since current inline measurement technology not yet provides the required accuracy, the Fraunhofer Institute for Laser Technology ILT is collaborating with four renowned industry partners in the INSPIRE project to develop inline sensors with a new accuracy class. Funded by the German Federal Ministry of Education and Research (BMBF), the project is scheduled to run until the end of 2019.

New Manufacturing Technologies for New Products

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

A new technique isolates neuronal activity during memory consolidation

22.06.2017 | Life Sciences

Plant inspiration could lead to flexible electronics

22.06.2017 | Materials Sciences

A rhodium-based catalyst for making organosilicon using less precious metal

22.06.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>