Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Dialysis Catheter Reduces Thrombus Accumulation

11.03.2010
r4 Vascular announces the commercial availability of the new DuraspanTM Biomimetic Coated long-term hemodialysis catheter.

A novel coating on the catheter surface mimics the glycocalyx layer found on natural endothelial tissue surfaces in vessel walls. Laboratory tests of the DuraspanTM catheter have demonstrated an 87% reduction in platelet adhesion and thrombus accumulation compared to uncoated catheters.

According to Kyle Smith, DO, Vascular Access Center of Southwest Louisiana, “Thrombus accumulation is one of the leading causes of failure among long-term hemodialysis catheters. Initially, thrombus may cause reduced flow rates, significantly decreasing the efficiency of even the largest catheters. Ultimately, thrombus may have catastrophic effects to the patient as it may prevent use of the venous access site for permanent forms of dialysis. My experience with DuraspanTM thus far has shown excellent performance and patency.”

Studies have shown almost 30% of prevalent hemodialysis patients use catheters for vascular access. Catheter complications are a major cause of morbidity and mortality for hemodialysis patients and increase the burden on the health care system. Surface treated catheters have been developed to combat the three most common causes of catheter failure: infection, fibrin sheath formation and thrombus formation. Thrombotic reducing coatings reduce platelet adhesion, inhibit the inflammatory response, and reduce thrombus formation on coronary stents, ventricular assist devices, central venous catheters, and vascular grafts.[1]

R4 is committed to improving dialysis patient catheter outcomes according to r4 Vascular’s President, Don Geer, “physicians have long thought that if one was able to make the catheter less recognizable as a foreign object in the body it could revolutionize catheter-based hemodialysis. Developing the catheter, r4 Vascular engineers utilized stealth coating technologies, approaching the thrombus problem by camouflaging the catheter in a biomimetic coating.” The catheter is available in either a 3.5cm tip stagger or a 7cm tip stagger version, providing reduced recirculation.

R4 will be “launching” sales of the catheter at the S.I.R. (Society of Interventional Radiology) conference March 13th through March 18th in Tampa, FL.

The DuraspanTM hemodialysis catheter is part of r4 Vascular’s technologically-advanced portfolio of products for the vascular access marketplace. In 2009, r4 Vascular launched the Zeus™ Biomimetic Coated CT PICC which is the first non-valved PICC to receive FDA clearance for saline-only maintenance, the company also launched the Pherocious Apheresis catheter which is the first power-injectable, triple lumen Apheresis catheter.

r4 Vascular is a privately-held vascular access company driving innovation in vascular access medical technology. r4's passion is “uncomplicating” venous access, chemotherapy, and drug delivery, through product improvements that help catheters remain patent and effective, with reduced risk of complications.

[1] Dwyer A. Reducing Tunneled Hemodialysis Catheter Morbidity : Surface Treated Catheters-A Review. Seminars in Dialysis-Vol 21, No 6 (November-December) 2008. 542-546.

Don Geer | r4 Vascular
Further information:
http://www.r4vascular.com

More articles from Medical Engineering:

nachricht Biocompatible 3-D tracking system has potential to improve robot-assisted surgery
17.02.2017 | Children's National Health System

nachricht Real-time MRI analysis powered by supercomputers
17.02.2017 | University of Texas at Austin, Texas Advanced Computing Center

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>