Rheumatoid arthritis is a long-term disease that leads to inflammation of the joints and surrounding tissues. Psoriatic arthritis is associated with psoriasis of the skin and is usually confined to the knees, ankles, and joints in the feet. "Clinically, it may be difficult to distinguish psoriatic arthritis from rheumatoid arthritis because the symptoms of both diseases are similar and the diagnostic tests currently available to aid in the differentiation of psoriatic and rheumatoid arthritis are not always sufficient," said Nina F. Schwenzer, MD, lead author of the study.
The study, performed at the University Hospital of Tubingen in Tubingen, Germany, included 45 patients (31 patients with rheumatoid arthritis and 14 with psoriatic arthritis) who were imaged using contrast-enhanced MRI. "The perfusion (or uptake) of contrast media in psoriatic arthritis and rheumatoid arthritis is presumed to be different," said Schwenzer. Typically, one will not be able to see a difference until after 15 minutes after the contrast material is given. "Our study revealed a significant difference in perfusion between those patients with rheumatoid arthritis and psoriatic arthritis after 15 minutes. However, since it was a small group of patients and there was an overlap in perfusion values between both types of arthritis, a diagnosis could not be led by contrast-enhanced MRI alone. Our results are nonetheless promising though," she said.
"In the past, the treatment strategy for patients with psoriatic arthritis was based on that for patients with rheumatoid arthritis. Recent research indicates that the therapeutic management, including medication and therapy monitoring, has to be adapted for each type of arthritis," said Schwenzer.
"As our study suggests, the use of contrast-enhanced MRI could play an important role in differentiating psoriatic arthritis from rheumatoid arthritis," she said.
This study appears in the March issue of the American Journal of Roentgenology. For a copy of the full study or to request an interview with Dr. Schwenzer, please contact Heather Curry via email at firstname.lastname@example.org or at 703-390-9822.
The American Roentgen Ray Society (ARRS) was founded in 1900 and is the oldest radiology society in the United States. Its monthly journal, the American Journal of Roentgenology, began publication in 1906. Radiologists from all over the world attend the ARRS annual meeting to participate in instructional courses, scientific paper presentations and scientific and commercial exhibits related to the field of radiology. The Society is named after the first Nobel Laureate in Physics, Wilhelm Röentgen, who discovered the x-ray in 1895.
Heather Curry | EurekAlert!
Artificial intelligence may help diagnose tuberculosis in remote areas
25.04.2017 | Radiological Society of North America
Pharmacoscpy: Next-Generation Microscopy
25.04.2017 | CeMM Forschungszentrum für Molekulare Medizin der Österreichischen Akademie der Wissenschaften
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Life Sciences
28.04.2017 | Life Sciences
28.04.2017 | Life Sciences