Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cancer risk of low dose ionizing radiation: new insights from modern biology provoke more questions and challenges

03.11.2008
Thanks to the European project RISC-RAD (Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiation), which has come to an end today, we now know more about the biological effects of low doses of ionizing radiation.

Started in January 2004, the project carried out research to contribute to the improvement of the management of health risks attributable to low dose exposures, i.e. 100 mSv or less.

New evidence concerning the processes that drive radiation carcinogenesis has been obtained. Some evidence was given that high and low dose responses can differ, and that a range of dose response relationships exist for cancer relevant phenomena. Animal models provide evidence of a link between direct radiation-induced genome change and cancer. Moreover non-targeted phenomena can also contribute.

Evidence was also gathered on the role of genetic factors in modifying risk in individuals and population sub-groups. These results do not point to a need to reconsider the use of LNT approaches to cancer risk projection but does highlight the complexity of the biological response to radiation at different dose levels particularly when considered at the level of the whole organism.

The consortium of 36 European partner labs focussed their efforts on radiation cancer risk and cover a wide range of scientific expertise from basic radiobiology through to cancer risk modelling. The project was supported by the European Commission Euratom programme with a contribution of 10 million Euro. It has overall harvested the resources of 31 institutions, 90 researchers, 28 post doctoral workers and 53 PhD students and an estimated overall project budget of 30 million Euro to address the problem of quantification of radiation cancer risk at low doses.

In the course of the project 163 scientific papers have been published and 51 PhD students trained. Wider outreach within the radiation protection community has been achieved through project members involvement in key radiation protection and radiobiology meetings such as UNSCEAR, IRPA, National health councils, Radiation Research, ESRB and the US Low Dose program meeting.

The results of the project and their relevance to radiation protection have been highlighted in a conference open to the public on October 8. Attended by about 100 people, it took place in the CEA research center in Fontenay-aux-Roses, France, the homeland of RISC-RAD and the workplace of the project coordinator, Laure Sabatier, who runs the laboratory of radiobiology and oncology in the Institute of Cellular and Molecular Radiobiology. The videos of the conference are accessible online from the following URL : www.riscrad.org

Two documents summarizing RISC-RAD research will be produced : “Improving the evidence base for radiation protection” and the scientific summary. Both will be available freely from November 2008 at www.riscrad.org.

Gaëlle Decroix | alfa
Further information:
http://www.riscrad.org

More articles from Medical Engineering:

nachricht Novel breast tomosynthesis technique reduces screening recall rate
21.02.2017 | Radiological Society of North America

nachricht Biocompatible 3-D tracking system has potential to improve robot-assisted surgery
17.02.2017 | Children's National Health System

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>