New ways to stretch DNA and other organic molecules
By taking advantage of the unique patterns generated when two immiscible fluids flow together, scientists have developed a new tool for studying tiny biomolecules.
Researchers at the National Taiwan University and the National Central University in Taiwan used a technique called two-phase microfluidics to stretch organic molecules in a systematic manner.
The researchers created different types of flow patterns by controlling wall wettability of a microfluidic channel, the flow rate ratio of two fluids, and the Reynolds number, which is a ratio between the inertial and viscous forces in a fluid.
By systematically varying these three parameters, the researchers could control the extension of a polymer string suspended in the fluid flow. Stretching polymers, proteins, DNA, and other organic macromolecules can reveal clues about what the molecules are made of and how they interact with other substances.
TITLE: "Polymer stretch in two-phase microfluidics: Effect of wall wettability"
AUTHORS: Ssu-Wei Hu (1), Yu-Jane Sheng (1), and Heng-Kwong Tsao (2)
(1) Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan
(2) Department of Chemical and Materials Engineering, Department of Physics, National Central University, Jhongli, Taiwan
Catherine Meyers | EurekAlert!
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers
Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...
Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.
At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...