Researchers at the University of North have discovered how hepatitis C binds with and repurposes a basic component of cellular metabolism known as a microRNA to help protect and replicate the virus.
A cultured liver cancer cell infected with Hepatitis C. The virus, stained red, surrounds the blue-stained nucleus and is in the process of being reproduced by virus within the cytoplasm. Photo courtesy of Takahiro Masaki/UNC Lemon Lab
A cultured liver cancer cell infected with Hepatitis C. The virus, stained red, surrounds the blue-stained nucleus and is in the process of being reproduced by virus within the cytoplasm. Photo courtesy of Takahiro Masaki/UNC Lemon LabIn a paper published online in the Proceedings of the National Academy of Sciences Dec. 17, researchers in the laboratory of Stanley M. Lemon, MD, professor of medicine and microbiology and immunology and member of UNC Lineberger Comprehensive Cancer Center, the Center for Translational Immunology, and the UNC Center for Infectious Disease, outline the critical role the microRNA known as miR-122 plays in the life cycle of the hepatitis C virus.
William Davis | EurekAlert!
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