Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

For the first time, the European IVF Monitoring Group reports on cycles using frozen eggs

06.07.2011
Other important data the European IVF Monitoring group (EIM) on 2008 cycles and the International Committee Monitoring Assisted Reproductive Technologies (ICMART) on 2007 cycles highlighted were Sweden's low rate of multiple births – the lowest in the world – and Spain's 30 % share of egg donations in Europe.

The EIM collected data on frozen oocyte retrieval (FOR) cycles for the first time. Until today, egg freezing is still not offered on a wide scale but can be an option for women who wish to postpone motherhood or are facing cancer therapy to save their lives.

Recently, vitrification techniques have offered oocyte survival rates in excess of 90 % and implantation rates per transfer that are comparable with fresh eggs. Scientists still face problems such as poor oocyte survival post-thaw, low fertilisation rates, cytoskeletal damage during vitrification and poor reproducibility of results.

"Of the 19 countries reporting on FOR in 2008, Italy is by far the country with the most cycles using this technology," said Dr. Jacques de Mouzon, chair of the EIM. With 3,284 cycles, Italy is far ahead of Finland (325 cycles), Russia (220) and Spain (199). The reason for Italy's dominance in this area lies in its legislative framework. A law passed in 2004 and overruled in 2009, set a limit of three oocytes to be inseminated per cycle, of which all resulting embryos had to be transferred. Embryo freezing and research on the embryo was outlawed, but not egg freezing. Hence, Italian clinics gained considerable expertise in this area over the last years.

The group also reported that with 4,068 cycles, 30 % of all egg donations (ED) occur in Spain, followed by the Czech Republic (15 %) and Russia (12 %). "Three countries make up almost 60 % of all egg donations in Europe," said Dr. De Mouzon. "Certain clinics in Spain offer wide-ranging egg donation programmes, which may also be the reason why Spain scores so high in terms of frozen oocyte cycles." This fact is mostly due to restrictive laws on ED in many countries, leading to many couples to cross borders to countries with less restrictive laws, which has raised an ethical and public health problem.

During the same scientific session, Dr. Karl Nygren, chair of ICMART, presented global ART data for 2007. "We are particularly pleased to present our data in Stockholm this year, since we can show that Sweden, a pioneer in enforcing single embryo transfer, has the world's lowest multiple birth rate with only 7 % twins and 0.1% of triplets being born after IVF and ICSI." Only Finland and Australia show comparably low rates with 9.3 % and 8.4% of twins, respectively, and almost no triplets. Many countries are still above 20 % for twin deliveries following IVF or ICSI such as for example Spain (23.8 %), Italy (21.2 %) and Germany (21.1 %) as are many Eastern European countries. "We would like to see more countries follow suit to decrease long-term complications for mother and child." The average rate in Europe was 20.6 % for twins and 1.1% for triplets in Europe.

According to data presented by the European IVF Monitoring Group (EIM), 525,640 treatment cycles were reported in 36 European countries. Four more countries reported in 2008 compared to 2007. This compares globally with 148,055 cycles from the US and 61,929 cycles from Australia and New Zealand. "We observed a 9.7 % increase in the number of cycles in Europe from 2007 to 2008, with only 21 more clinics reporting to our database," said Dr. Jacques de Mouzon, chairman of ESHRE's EIM. The delivery rate (DR) per aspiration was 22.1% for IVF and 21.1% for ICSI. DR per transfer was 14.5% for FET and 28.5% for ED. All these rates were relatively stable compared to the previous year, as was the multiple deliveries proportion.

In 30 countries where clinics reported deliveries, 80,284 babies were born. "We believe this to be an underestimate since data on deliveries for Turkey, Poland and some other countries were still missing." There were 124,749 IVF treatments, 280,977 intracytoplasmic sperm injection (ICSI) cycles, 98,288 frozen embryo transfer cycles (FER), 13,609 egg donor cycles (ED), 4,080 FOR, 2,875 preimplantation genetic diagnosis/screening cycles (PGD/PGS) and 1,062 in vitro maturation cycles (IVM).

In terms of ART availability, the largest economies in Europe such as France (5,464 cycles per million women of reproductive age), Italy (4,015), Spain (3,845), the Netherlands (6,382), Germany (4,810) and the UK (4,066) still show much lower availabilities of ART compared to their Nordic neighbours such as Sweden (9,228), Norway (9,287), Denmark (12,712) and Finland (9,291). This is also mirrored in the number of infants born after ART with only 1.7 % in Spain, 2.4 % in the Netherlands, 1.4 % in Germany and 1.9 % in the UK compared to 3.3 % in Sweden, 2.4 % in Norway and 3.0 % in Finland. For Denmark figures were not available yet. Also, 25 countries reported 146,741 IUI-H (with husband's sperm) and 24, 895 IUI-D (donor sperm), with a multiple pregnancy rate (11.1% twin and 0.8 triplet for women aged less than 40 years) not higher than in IVF and ICSI.

U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), Assisted Reproduction Technology Success Rates, National Summary and Fertility Clinic Reports, December 2010 at http://www.cdc.gov/art/ART2008/PDF/ART_2008_Full.pdf

AIHW (2010) Australian Institute of Health and Welfare, Assisted Reproduction Technology in Australia and New Zealand 2008. National Perinatal Statistical Unit and Fertility Society of Australia. Assisted Reproduction Technology Series, number 14, at http://www.aihw.gov.au/publication-detail/?id=6442468391&tab=2

Full pdfs of these references are available on request.

Abstract no: Dr. De Mouzon O-208 Wednesday 6 July 2011, 8.30 hrs CEST (Hall A1)
Dr. Nygren O-209 Wednesday 6 July 2011, 8.50 hrs CEST (Hall A1)
Note: When obtaining outside comment, journalists are requested to ensure that their contacts are aware of the embargo on this release.

For further information on the details contained in this press release, contact:

In English, German, Spanish, French
Hanna Hanssen
Tel: +32 (0) 263 64 66
Mobile: + 32 (0) 473 35 33 81
Email: hanna@eshre.eu
If unavailable, or for general information about the conference contact:
In English and French
Mary Rice
Tel: +33 (0)3 85 28 26 63
Mobile: +33 (0)6 68 93 06 50
Email: mary.rice@riceconseil.eu

Hanna Hanssen | EurekAlert!
Further information:
http://www.eshre.eu

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>