Researchers in the United Kingdom and Malaysia are developing a new class of injectable material that stimulates stem cells to regenerate damaged tissue and form new blood vessels, heart and bone tissue.
Their aim is to produce radical new treatments that will reduce the need for invasive surgery, optimise recovery and reduce the risk of undesirable scar tissue.
The research, which brings together expertise at the University of Nottingham and its Malaysia Campus (UNMC), is part of the “Rational Bioactive Materials Design for Tissue Generation” or “Biodesign” project – an €11m EU-funded initiative involving 21 research teams from across Europe.
“This research heralds a step-change in approaches to tissue regeneration,” says Professor Kevin Shakesheff, Head of the School of Pharmacy at the University of Nottingham's UK campus.
“Current biomaterials are poorly suited to the needs of tissue engineering and regenerative medicine. Our aim is to develop new materials and medicines that will stimulate tissue regeneration rather than wait for the body to start the process itself.”
UNMC is building on its expertise in nanotechnology for drug delivery. “Here in Malaysia we are looking at synthesising microparticles that can be injected directly into a patient at the site of injury to promote tissue re-growth,” says Professor Andrew Morris, an expert in transdermal drug delivery and Head of the School of Pharmacy (UNMC). “These microparticles would act as a scaffold to encourage regrowth in bone tissue, skeletal muscle and potentially even cardiac muscle.”
This research is going to have a significant impact on patients,” says Dr. Nashiru Billa who is the Associate Dean for Research in the Faculty of Science. “In future, you could include anti-cancer drugs in the delivery system that would not only lead to the growth of the tissue but would also help kill cancer cells within the bone tissue.”
For more information contact:
PR & Communications Manager
Tel: +60 (03) 8924 8746
Dr. Nashiru Billa
Tel: +60 (03) 8924 8211.
Notes to editors:
The University of Nottingham has 43,000 students and is ‘the nearest Britain has to a truly global university, with campuses in China and Malaysia modelled on a headquarters that is among the most attractive in Britain’ (Times Good University Guide 2014). It is also the most popular university in the UK among graduate employers, one of the world’s greenest universities, and winner of the Times Higher Education Award for ‘Outstanding Contribution to Sustainable Development’. It is ranked in the World’s Top 75 universities by the QS World University Rankings.
Two decades of training students and experts in tracking infectious disease
27.11.2015 | Hochschule für Angewandte Wissenschaften Hamburg
Increased carbon dioxide enhances plankton growth, opposite of what was expected
27.11.2015 | Bigelow Laboratory for Ocean Sciences
Planet Earth experienced a global climate shift in the late 1980s on an unprecedented scale, fuelled by anthropogenic warming and a volcanic eruption, according to new research published this week.
Scientists say that a major step change, or ‘regime shift’, in the Earth’s biophysical systems, from the upper atmosphere to the depths of the ocean and from...
The Fraunhofer Institute for Solar Energy Systems ISE has installed 70 photovoltaic modules on the outer façade of one of its lab buildings. The modules were...
Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.
In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid...
In laser material processing, the simulation of processes has made great strides over the past few years. Today, the software can predict relatively well what will happen on the workpiece. Unfortunately, it is also highly complex and requires a lot of computing time. Thanks to clever simplification, experts from Fraunhofer ILT are now able to offer the first-ever simulation software that calculates processes in real time and also runs on tablet computers and smartphones. The fast software enables users to do without expensive experiments and to find optimum process parameters even more effectively.
Before now, the reliable simulation of laser processes was a job for experts. Armed with sophisticated software packages and after many hours on computer...
Researchers at Heidelberg University have devised a new way to study the phenomenon of magnetism. Using ultracold atoms at near absolute zero, they prepared a...
25.11.2015 | Event News
17.11.2015 | Event News
21.10.2015 | Event News
27.11.2015 | Press release
27.11.2015 | Life Sciences
27.11.2015 | Materials Sciences